Literature DB >> 10394417

Dosimetry of the boron neutron capture reaction for BNCT and BNCEFNT.

J Burmeister1, C Kota, R L Maughan.   

Abstract

The use of paired proportional counters, constructed from A-150 tissue equivalent plastic (TEP) and A-150 TEP loaded with an appropriate amount of 10B (50 to 200 ppm), for the dosimetry of the boron neutron capture reaction has been investigated for several years at the Gershenson Radiation Oncology Center. This method has been used for determining the dose components (fast neutron, gamma ray and boron capture product dose) in both Boron Neutron Capture Therapy (BNCT) beams and in beams proposed for boron neutron capture enhancement of fast neutron therapy (BNCEFNT). A disadvantage of this method, when standard 1/2" diameter Rossi type proportional counters are used, is that the beam intensity must be relatively low in order to avoid saturation effects (pulse pile-up) in the counter. This is a major problem if measurements are to be made in a reactor beam, since reducing the beam intensity generally results in a change in the neutron spectrum. In order to overcome this problem, miniature cylindrical proportional counters have been developed which may be used in high intensity beams. The operational characteristics of these counters are compared with the standard 1/2" spherical counters. A further disadvantage of proportional counters is the relatively long time it takes to collect data, particularly if detailed information (depth-dose curves and beam profiles) is required. This problem could be overcome by using a set of ionization chambers (an A-150 TEP chamber, a Mg chamber and a Mg chamber with a 25 microns boron loaded inner wall) which can be scanned in a water phantom. After calibration against the paired proportional counters it should be possible to extract the fast neutron, gamma ray and boron neutron capture product doses from measurements made with these three ionization chambers. A set of such chambers has been used to make preliminary measurements in a fast neutron beam and the results of these measurements are presented.

Entities:  

Mesh:

Year:  1999        PMID: 10394417     DOI: 10.1007/bf03038908

Source DB:  PubMed          Journal:  Strahlenther Onkol        ISSN: 0179-7158            Impact factor:   3.621


  3 in total

1.  Microdosimetry for boron neutron capture therapy.

Authors:  C S Wuu; H I Amols; P Kliauga; L E Reinstein; S Saraf
Journal:  Radiat Res       Date:  1992-06       Impact factor: 2.841

2.  The influence of the counter wall and the counter shape on the spectral energy deposition in small volumes by 60Co gamma-rays and 200 kV x-rays.

Authors:  R Eickel; J Booz
Journal:  Radiat Environ Biophys       Date:  1976-07-30       Impact factor: 1.925

3.  Determination of the thermal neutron flux in a fast neutron beam by use of a boron-coated ionization chamber.

Authors:  L Lüdemann; T Matzen; M Matzke; R Schmidt; W Scobel
Journal:  Med Phys       Date:  1995-11       Impact factor: 4.071

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.