Literature DB >> 10380184

Linear modeling of mRNA expression levels during CNS development and injury.

P D'haeseleer1, X Wen, S Fuhrman, R Somogyi.   

Abstract

Large-scale gene expression data sets are revolutionizing the field of functional genomics. However, few data analysis techniques fully exploit this entirely new class of data. We present a linear modeling approach that allows one to infer interactions between all the genes included in the data set. The resulting model can be used to generate interesting hypotheses to direct further experiments.

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Year:  1999        PMID: 10380184     DOI: 10.1142/9789814447300_0005

Source DB:  PubMed          Journal:  Pac Symp Biocomput        ISSN: 2335-6928


  79 in total

1.  Dynamic modeling of gene expression data.

Authors:  N S Holter; A Maritan; M Cieplak; N V Fedoroff; J R Banavar
Journal:  Proc Natl Acad Sci U S A       Date:  2001-02-13       Impact factor: 11.205

2.  Reverse engineering gene networks using singular value decomposition and robust regression.

Authors:  M K Stephen Yeung; Jesper Tegnér; James J Collins
Journal:  Proc Natl Acad Sci U S A       Date:  2002-04-30       Impact factor: 11.205

Review 3.  A framework for integrating the songbird brain.

Authors:  E D Jarvis; V A Smith; K Wada; M V Rivas; M McElroy; T V Smulders; P Carninci; Y Hayashizaki; F Dietrich; X Wu; P McConnell; J Yu; P P Wang; A J Hartemink; S Lin
Journal:  J Comp Physiol A Neuroethol Sens Neural Behav Physiol       Date:  2002-11-15       Impact factor: 1.836

4.  Comparing the continuous representation of time-series expression profiles to identify differentially expressed genes.

Authors:  Ziv Bar-Joseph; Georg Gerber; Itamar Simon; David K Gifford; Tommi S Jaakkola
Journal:  Proc Natl Acad Sci U S A       Date:  2003-08-21       Impact factor: 11.205

5.  Identification of genetic networks.

Authors:  Momiao Xiong; Jun Li; Xiangzhong Fang
Journal:  Genetics       Date:  2004-02       Impact factor: 4.562

6.  Gene set enrichment; a problem of pathways.

Authors:  Matthew N Davies; Emma L Meaburn; Leonard C Schalkwyk
Journal:  Brief Funct Genomics       Date:  2010-09-22       Impact factor: 4.241

7.  Dynamics of cellular level function and regulation derived from murine expression array data.

Authors:  Benjamin de Bivort; Sui Huang; Yaneer Bar-Yam
Journal:  Proc Natl Acad Sci U S A       Date:  2004-12-14       Impact factor: 11.205

Review 8.  Systems interface biology.

Authors:  Francis J Doyle; Jörg Stelling
Journal:  J R Soc Interface       Date:  2006-10-22       Impact factor: 4.118

9.  A linear programming approach for estimating the structure of a sparse linear genetic network from transcript profiling data.

Authors:  Sahely Bhadra; Chiranjib Bhattacharyya; Nagasuma R Chandra; I Saira Mian
Journal:  Algorithms Mol Biol       Date:  2009-02-24       Impact factor: 1.405

10.  Transcription factor network reconstruction using the living cell array.

Authors:  Eric Yang; Martin L Yarmush; Ioannis P Androulakis
Journal:  J Theor Biol       Date:  2008-10-22       Impact factor: 2.691

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