Literature DB >> 10377289

The trithorax-group and polycomb-group chromatin modifiers: implications for disease.

M van Lohuizen1.   

Abstract

The chromatin structure associated transcriptional memory function by Polycomb-group and trithorax-group protein complexes integrate normal development with control of cellular proliferation. This is illustrated by recent mechanistic insights that link Polycomb repression with histone deacetylases and the identification of new target genes that provide a connection to cell cycle control and tumorigenesis.

Mesh：

Substances：

Year:  1999        PMID： 10377289     DOI： 10.1016/s0959-437x(99)80053-7

Source DB:  PubMed          Journal:  Curr Opin Genet Dev        ISSN： 0959-437X            Impact factor:   5.578


  17 in total

1.  The MT domain of the proto-oncoprotein MLL binds to CpG-containing DNA and discriminates against methylation.

Authors:  Marco Birke; Silke Schreiner; María-Paz García-Cuéllar; Kerstin Mahr; Fritz Titgemeyer; Robert K Slany
Journal:  Nucleic Acids Res       Date:  2002-02-15       Impact factor: 16.971

2.  RING1 inhibits transactivation of RBP-J by Notch through interaction with LIM protein KyoT2.

Authors:  Hongyan Qin; Jishu Wang; Yingmin Liang; Yoshihito Taniguchi; Kenji Tanigaki; Hua Han
Journal:  Nucleic Acids Res       Date:  2004-03-03       Impact factor: 16.971

3.  Bmi1 facilitates primitive endoderm formation by stabilizing Gata6 during early mouse development.

Authors:  Fabrice Lavial; Sylvain Bessonnard; Yusuke Ohnishi; Akiko Tsumura; Anil Chandrashekran; Mark A Fenwick; Rute A Tomaz; Hiroyuki Hosokawa; Toshinori Nakayama; Ian Chambers; Takashi Hiiragi; Claire Chazaud; Véronique Azuara
Journal:  Genes Dev       Date:  2012-06-19       Impact factor: 11.361

4.  The Arabidopsis homolog of trithorax, ATX1, binds phosphatidylinositol 5-phosphate, and the two regulate a common set of target genes.

Authors:  Raul Alvarez-Venegas; Monther Sadder; Andrej Hlavacka; Frantisek Baluska; Yuannan Xia; Guoqing Lu; Alexey Firsov; Gautam Sarath; Hideaki Moriyama; Joseph G Dubrovsky; Zoya Avramova
Journal:  Proc Natl Acad Sci U S A       Date:  2006-04-03       Impact factor: 11.205

5.  Bmi-1 collaborates with c-Myc in tumorigenesis by inhibiting c-Myc-induced apoptosis via INK4a/ARF.

Authors:  J J Jacobs; B Scheijen; J W Voncken; K Kieboom; A Berns; M van Lohuizen
Journal:  Genes Dev       Date:  1999-10-15       Impact factor: 11.361

Review 6.  Mechanisms of Yin Yang 1 in oncogenesis: the importance of indirect effects.

Authors:  Michael Atchison; Arindam Basu; Kristina Zaprazna; Madhusudhan Papasani
Journal:  Crit Rev Oncog       Date:  2011

7.  Essential role of Drosophila Hdac1 in homeotic gene silencing.

Authors:  Y L Chang; Y H Peng; I C Pan; D S Sun; B King; D H Huang
Journal:  Proc Natl Acad Sci U S A       Date:  2001-08-07       Impact factor: 11.205

8.  STAT6-mediated displacement of polycomb by trithorax complex establishes long-term maintenance of GATA3 expression in T helper type 2 cells.

Authors:  Atsushi Onodera; Masakatsu Yamashita; Yusuke Endo; Makoto Kuwahara; Soichi Tofukuji; Hiroyuki Hosokawa; Akinori Kanai; Yutaka Suzuki; Toshinori Nakayama
Journal:  J Exp Med       Date:  2010-10-18       Impact factor: 14.307

9.  Transvection and silencing of the Scr homeotic gene of Drosophila melanogaster.

Authors:  Jeffrey W Southworth; James A Kennison
Journal:  Genetics       Date:  2002-06       Impact factor: 4.562

10.  Polycomb-group proteins are involved in silencing processes caused by a transgenic element from the murine imprinted H19/Igf2 region in Drosophila.

Authors:  Sylvia Erhardt; Frank Lyko; Justin F-X Ainscough; M Azim Surani; Renato Paro
Journal:  Dev Genes Evol       Date:  2003-05-15       Impact factor: 0.900
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.