Literature DB >> 1037211

The synthesis of ethyl apovincaminate.

C Lörincz, K Szász, L Kisfaludy.   

Abstract

Starting from (+) vincamine (I), simple derivatives of vincaminic acid (II), apovincaminic acid (V) and apovincaminol (VII) were synthetized. Out of these the synthesis of ethyl apovincaminate (Cavinton), as a representative, is described in detail. The water elimination and esterification of II can be carried out in one step.

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Year:  1976        PMID: 1037211

Source DB:  PubMed          Journal:  Arzneimittelforschung        ISSN: 0004-4172


  6 in total

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  6 in total

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