| Literature DB >> 10371459 |
K P Whittall1, A L MacKay, D K Li.
Abstract
T2 relaxation decay curves from in vivo human brain tissue are rarely mono-exponential. Partial volume averaging further reduces the chance of mono-exponential decay. Moreover, the parameters derived from few-echo mono-exponential fits change with the measurement echo times and have the largest possible variance. In this note, multi-exponential fits to 32-echo relaxation decay curves from in vivo human brain are used to design simulations (where the truth is known) to demonstrate the pitfalls of few-echo mono-exponential interpretations.Entities:
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Year: 1999 PMID： 10371459 DOI： 10.1002/(sici)1522-2594(199906)41:6<1255::aid-mrm23>3.0.co;2-i
Source DB: PubMed Journal: Magn Reson Med ISSN： 0740-3194 Impact factor: 4.668