Literature DB >> 10364974

An audit of the investigation and treatment of localised prostatic cancer in the south west region.

R N Lodge1.   

Abstract

Prostate cancer constitutes a major health care dilemma in terms of treatment options available and increasing patient load on both a regional and national level. An audit was undertaken of all patients in the South West Region with localised prostate cancer newly diagnosed in 1993 to assess regional management of this disease. In 1993, 1407 patients were newly diagnosed as having prostatic cancer. Patients > 75 years old and those with a prostate-specific antigen (PSA) > 40 ng/ml were excluded, leaving 262 patients whose case notes were examined. The interval between referral and clinic (mean 67 days) was altered by the presence of a GP performed PSA, being shorter if the PSA was > 10 ng/ml (average 54 days) than if the PSA was < 10 ng/ml (average 104 days). Overall, 34% of patients underwent radical treatment (10% radical prostatectomy and 24% radiotherapy). In all, 27% received hormone manipulation or orchidectomy, and the remainder 'watchful waiting'. The majority (78%) of patients < 60 years old received radical treatment, as did 35% of those 60-70 years and 15% of 70-75 year olds. Over 90% of tumours were category T1 and were well or moderately differentiated. All patients had a histological diagnosis and 84% had their tumour staged before treatment. This study highlighted the need for improvements in patient assessment, improved note keeping and a regional cancer register to allow ongoing assessment of patient management. This audit of management of localised prostate cancer serves as a baseline from which to initiate and monitor improvements in the service regionally and will also allow assessment of the impact of such changes.

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Year:  1999        PMID: 10364974      PMCID: PMC2503217     

Source DB:  PubMed          Journal:  Ann R Coll Surg Engl        ISSN: 0035-8843            Impact factor:   1.891


  17 in total

1.  Diagnosis of prostate cancer: a personal view.

Authors:  T A Stamey
Journal:  J Urol       Date:  1992-03       Impact factor: 7.450

Review 2.  Update on the appropriate staging evaluation for newly diagnosed prostate cancer.

Authors:  G J O'Dowd; R W Veltri; R Orozco; M C Miller; J E Oesterling
Journal:  J Urol       Date:  1997-09       Impact factor: 7.450

Review 3.  Combined androgen blockade: an optimal therapy for minimally advanced prostate cancer?

Authors:  M S Soloway
Journal:  Br J Urol       Date:  1998-01

4.  High 10-year survival rate in patients with early, untreated prostatic cancer.

Authors:  J E Johansson; H O Adami; S O Andersson; R Bergström; L Holmberg; U B Krusemo
Journal:  JAMA       Date:  1992 Apr 22-29       Impact factor: 56.272

5.  An algorithm for predicting nonorgan confined prostate cancer using the results obtained from sextant core biopsies with prostate specific antigen level.

Authors:  R A Badalament; M C Miller; P A Peller; D C Young; D K Bahn; P Kochie; G J O'Dowd; R W Veltri
Journal:  J Urol       Date:  1996-10       Impact factor: 7.450

6.  Experience with an assay for prostate-specific antigen and transrectal ultrasonography in the diagnosis of prostate cancer.

Authors:  C A Heman-Ackah; J B Festenstein; P Hibbert; D J Harvey; C J Bunce; J S Gelister
Journal:  Br J Urol       Date:  1997-03

7.  A decision analysis of alternative treatment strategies for clinically localized prostate cancer. Prostate Patient Outcomes Research Team.

Authors:  C Fleming; J H Wasson; P C Albertsen; M J Barry; J E Wennberg
Journal:  JAMA       Date:  1993-05-26       Impact factor: 56.272

8.  Prostate cancer screening: what we know and what we need to know.

Authors:  B S Kramer; M L Brown; P C Prorok; A L Potosky; J K Gohagan
Journal:  Ann Intern Med       Date:  1993-11-01       Impact factor: 25.391

Review 9.  Recent results of management of palpable clinically localized prostate cancer.

Authors:  J Adolfsson; G Steineck; W F Whitmore
Journal:  Cancer       Date:  1993-07-15       Impact factor: 6.860

10.  Expectant management of localized prostatic cancer.

Authors:  W F Whitmore; J A Warner; I M Thompson
Journal:  Cancer       Date:  1991-02-15       Impact factor: 6.860

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  1 in total

1.  Accuracy and cost of intraoperative lymph node frozen sections at radical prostatectomy.

Authors:  M P Young; R S Kirby; E P O'Donoghue; M C Parkinson
Journal:  J Clin Pathol       Date:  1999-12       Impact factor: 3.411

  1 in total

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