Literature DB >> 10354659

Is atypical depression a moderate severity depression? A 536-case study.

F Benazzi1.   

Abstract

OBJECTIVE: To determine if atypical depression is less common among outpatients with severe depression than among those with nonsevere depression.
DESIGN: Case series.
SETTING: Private practice. PATIENTS: Five hundred and thirty-six consecutive outpatients presenting for treatment of unipolar or bipolar II depression. OUTCOME MEASURES: Prevalence of atypical depression among patients with severe depression (Global Assessment of Functioning Scale [GAF] score of 50 or less) and nonsevere depression.
RESULTS: There was no significant difference in the prevalence of atypical depression between patients with severe and nonsevere depression.
CONCLUSIONS: Results do not support previous studies that atypical depression is usually of moderate severity. A rating scale like the GAF, which assesses both symptom severity and impairment of functioning, may give a more complete assessment of depression severity than a symptoms rating scale (used in previous studies), which does not cover atypical features and does not assess functioning.

Entities:  

Mesh:

Year:  1999        PMID: 10354659      PMCID: PMC1189015     

Source DB:  PubMed          Journal:  J Psychiatry Neurosci        ISSN: 1180-4882            Impact factor:   6.186


  15 in total

1.  Algorithms for the treatment of subtypes of unipolar major depression.

Authors:  J C Nelson; J P Docherty; G M Henschen; S Kasper; A A Nierenberg; N G Ward
Journal:  Psychopharmacol Bull       Date:  1995

2.  Controversies in the diagnosis and treatment of severe depression.

Authors: 
Journal:  J Clin Psychiatry       Date:  1996-11       Impact factor: 4.384

3.  The identification and validation of distinct depressive syndromes in a population-based sample of female twins.

Authors:  K S Kendler; L J Eaves; E E Walters; M C Neale; A C Heath; R C Kessler
Journal:  Arch Gen Psychiatry       Date:  1996-05

4.  Phenelzine and imipramine in mood reactive depressives. Further delineation of the syndrome of atypical depression.

Authors:  F M Quitkin; P J McGrath; J W Stewart; W Harrison; S G Wager; E Nunes; J G Rabkin; E Tricamo; J Markowitz; D F Klein
Journal:  Arch Gen Psychiatry       Date:  1989-09

5.  Response to phenelzine and imipramine in placebo nonresponders with atypical depression. A new application of the crossover design.

Authors:  F M Quitkin; W Harrison; J W Stewart; P J McGrath; E Tricamo; K Ocepek-Welikson; J G Rabkin; S G Wager; E Nunes; D F Klein
Journal:  Arch Gen Psychiatry       Date:  1991-04

Review 6.  The prevalent clinical spectrum of bipolar disorders: beyond DSM-IV.

Authors:  H S Akiskal
Journal:  J Clin Psychopharmacol       Date:  1996-04       Impact factor: 3.153

7.  Atypical depression.

Authors:  J R Davidson; R D Miller; C D Turnbull; J L Sullivan
Journal:  Arch Gen Psychiatry       Date:  1982-05

8.  A new depression scale designed to be sensitive to change.

Authors:  S A Montgomery; M Asberg
Journal:  Br J Psychiatry       Date:  1979-04       Impact factor: 9.319

9.  Chronic depression: response to placebo, imipramine, and phenelzine.

Authors:  J W Stewart; P J McGrath; F M Quitkin; J G Rabkin; W Harrison; S Wager; E Nunes; K Ocepek-Welikson; E Tricamo
Journal:  J Clin Psychopharmacol       Date:  1993-12       Impact factor: 3.153

10.  National Institute of Mental Health Treatment of Depression Collaborative Research Program. General effectiveness of treatments.

Authors:  I Elkin; M T Shea; J T Watkins; S D Imber; S M Sotsky; J F Collins; D R Glass; P A Pilkonis; W R Leber; J P Docherty
Journal:  Arch Gen Psychiatry       Date:  1989-11
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  3 in total

1.  Epidemiology of major depression with atypical features: results from the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC).

Authors:  Carlos Blanco; Oriana Vesga-López; Jonathan W Stewart; Shang-Min Liu; Bridget F Grant; Deborah S Hasin
Journal:  J Clin Psychiatry       Date:  2011-09-06       Impact factor: 4.384

2.  Early- versus late-onset bipolar II disorder.

Authors:  F Benazzi
Journal:  J Psychiatry Neurosci       Date:  2000-01       Impact factor: 6.186

3.  Atypical depression.

Authors:  Tanvir Singh; Kristi Williams
Journal:  Psychiatry (Edgmont)       Date:  2006-04
  3 in total

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