Literature DB >> 10348779

Effect of HSR-903, a new fluoroquinolone, on the concentration of theophylline in serum.

Y Niki1, S Watanabe, S Tamada, K Yoshida, N Miyashita, M Nakajima, T Matsushima, H Sekino, O Matsuoka.   

Abstract

The effect of HSR-903, a new fluoroquinolone, on the concentration of theophylline in serum in healthy male volunteers was investigated. The concentration of theophylline in serum and the urinary excretion rates of theophylline on day 5 of concomitant dosing with HSR-903 tended to increase compared to those on day 4, when theophylline was given alone; however, the urinary excretion rates of 1-methyluric acid and 3-methylxanthine on day 5 of concomitant dosing with HSR-903 tended to decrease in comparison to those on day 4, when theophylline was given alone.

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Year:  1999        PMID： 10348779      PMCID： PMC89305          DOI： 10.1128/AAC.43.6.1494

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  5 in total

1.  In vitro activity of HSR-903, a new quinolone.

Authors:  Y Takahashi; N Masuda; M Otsuki; M Miki; T Nishino
Journal:  Antimicrob Agents Chemother       Date:  1997-06       Impact factor: 5.191

2.  Determination of the urinary metabolites of caffeine and theophylline by high-performance liquid chromatography. A comparative study of a direct injection and an ion-pair extraction procedure.

Authors:  N R Scott; J Chakraborty; V Marks
Journal:  J Chromatogr       Date:  1986-03-07

3.  Quinolones and raised plasma concentrations of theophylline.

Authors:  F P Maesen; J P Teengs; C Baur; B I Davies
Journal:  Lancet       Date:  1984-09-01       Impact factor: 79.321

4.  Enoxacin raises plasma theophylline concentrations.

Authors:  W J Wijnands; C L van Herwaarden; T B Vree
Journal:  Lancet       Date:  1984-07-14       Impact factor: 79.321

5.  In vitro and in vivo antichlamydial activities of HSR-903, a new fluoroquinolone antibiotic.

Authors:  Y Niki; N Miyashita; Y Kubota; M Nakajima; T Matsushima
Journal:  Antimicrob Agents Chemother       Date:  1997-04       Impact factor: 5.191
  5 in total
  1 in total

Review 1.  Comparative tolerability of the newer fluoroquinolone antibacterials.

Authors:  P Ball; L Mandell; Y Niki; G Tillotson
Journal:  Drug Saf       Date:  1999-11       Impact factor: 5.606
  1 in total

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