Literature DB >> 10338144

pADPRT-2: a novel mammalian polymerizing(ADP-ribosyl)transferase gene related to truncated pADPRT homologues in plants and Caenorhabditis elegans.

H Berghammer1, M Ebner, R Marksteiner, B Auer.   

Abstract

Until recently, poly(ADP-ribosyl)ation was supposed to be confined only to polymerizing(ADP-ribosyl)transferase/(ADP-ribose)polymerase (E.C. 2.4.2.30). Here, we present novel polymerizing(ADP-ribosyl)transferase homologues from mouse and man that lack all of the N-terminal DNA binding and BRCA1 C-terminus domains and will be designated polymerizing(ADP-ribosyl)transferase-2 as distinguished from the classical polymerizing(ADP-ribosyl)transferase (polymerizing(ADP-ribosyl)transferase-1). The murine polymerizing(ADP-ribosyl)transferase-2 gene shares three identical intron positions with its Caenorhabditis elegans (EMBL nucleotide sequence database Z47075) and one with the Arabidopsis thaliana homologue ('APP', GenBank database AF069298). Expression of the murine polymerizing(ADP-ribosyl)transferase-2 gene was elevated in spleen, thymus and testis and the corresponding poly(ADP-ribosyl)ation activity might account for most of the residual poly(ADP-ribosyl)ation observed in polymerizing(ADP-ribosyl)transferase-1(-/-) mice.

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Year:  1999        PMID： 10338144     DOI： 10.1016/s0014-5793(99)00448-2

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  8 in total

1.  Cytokine-mediated β-cell damage in PARP-1-deficient islets.

Authors:  Teresa Andreone; Gordon P Meares; Katherine J Hughes; Polly A Hansen; John A Corbett
Journal:  Am J Physiol Endocrinol Metab       Date:  2012-04-24       Impact factor: 4.310

Review 2.  Coordination of DNA single strand break repair.

Authors:  Rachel Abbotts; David M Wilson
Journal:  Free Radic Biol Med       Date:  2016-11-24       Impact factor: 7.376

3.  Syncytiotrophoblastic giant cells in teratocarcinoma-like tumors derived from Parp-disrupted mouse embryonic stem cells.

Authors:  T Nozaki; M Masutani; M Watanabe; T Ochiya; F Hasegawa; H Nakagama; H Suzuki; T Sugimura
Journal:  Proc Natl Acad Sci U S A       Date:  1999-11-09       Impact factor: 11.205

4.  PARP-1 and PARP-2: New players in tumour development.

Authors:  José Yelamos; Jordi Farres; Laura Llacuna; Coral Ampurdanes; Juan Martin-Caballero
Journal:  Am J Cancer Res       Date:  2011-01-08       Impact factor: 6.166

5.  Poly(ADP-ribosyl)ation basally activated by DNA strand breaks reflects glutamate-nitric oxide neurotransmission.

Authors:  A A Pieper; S Blackshaw; E E Clements; D J Brat; D K Krug; A J White; P Pinto-Garcia; A Favit; J R Conover; S H Snyder; A Verma
Journal:  Proc Natl Acad Sci U S A       Date:  2000-02-15       Impact factor: 11.205

Review 6.  New paradigms in the repair of oxidative damage in human genome: mechanisms ensuring repair of mutagenic base lesions during replication and involvement of accessory proteins.

Authors:  Arijit Dutta; Chunying Yang; Shiladitya Sengupta; Sankar Mitra; Muralidhar L Hegde
Journal:  Cell Mol Life Sci       Date:  2015-01-10       Impact factor: 9.261

7.  The genes pme-1 and pme-2 encode two poly(ADP-ribose) polymerases in Caenorhabditis elegans.

Authors:  Steve N Gagnon; Michael O Hengartner; Serge Desnoyers
Journal:  Biochem J       Date:  2002-11-15       Impact factor: 3.857

8.  Crystal structure of the catalytic fragment of murine poly(ADP-ribose) polymerase-2.

Authors:  Antony W Oliver; Jean-Christophe Amé; S Mark Roe; Valerie Good; Gilbert de Murcia; Laurence H Pearl
Journal:  Nucleic Acids Res       Date:  2004-01-22       Impact factor: 16.971
  8 in total

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