| Literature DB >> 10327208 |
H Braak1, D Sandmann-Keil, W Gai, E Braak.
Abstract
Lewy bodies and coarse Lewy neurites are the pathological hallmarks of degenerating neurons in the brains of patients suffering from Parkinson's disease (PD). Recently, the presynaptic protein alpha-synuclein was shown to be a major component of Lewy bodies and Lewy neurites. This study demonstrates for the first time that extensive and thin alpha-synuclein-immunoreactive inclusions are present in the axonal processes of neurons.Entities:
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Year: 1999 PMID： 10327208 DOI： 10.1016/s0304-3940(99)00208-6
Source DB: PubMed Journal: Neurosci Lett ISSN： 0304-3940 Impact factor: 3.046