Literature DB >> 10232626

Enhanced postprandial energy expenditure with medium-chain fatty acid feeding is attenuated after 14 d in premenopausal women.

M D White1, A A Papamandjaris, P J Jones.   

Abstract

BACKGROUND: Medium-chain triacylglycerols (MCTs) are reported to enhance human energy expenditure (EE), although few studies have involved women and the duration of such effects is only known for periods of approximately 7 d.
OBJECTIVE: This study was conducted to determine whether women consuming mixed, MCT-enriched or long-chain triacylglycerol (LCT)-enriched diets showed changes in EE or substrate oxidation after 7 and 14 d.
DESIGN: Twelve nonobese, premenopausal women were fed isoenergetic mixed diets enriched in either MCTs or LCTs during separate, 14-d feeding periods. Each meal contained 40% of energy as fat (80% of which was the treatment fat), 45% as carbohydrate, and 15% as protein. On days 7 and 14 of each trial, basal metabolic rate (BMR, kJ/min), total energy expenditure (TEE, kJ/min), and thermic effect of feeding (deltakJ/min) after a standardized breakfast were measured by respiratory gas exchange.
RESULTS: On day 7, the mean (+/-SEM) BMR (3.58+/-0.11 kJ/min) with the MCT diet was greater (P = 0.0003) than that with the LCT diet (3.43+/-0.11 kJ/min). The mean postprandial TEE on day 7 was significantly greater (P = 0.04) with the MCT diet (4.36+/-0.04 kJ/min) than with the LCT diet (4.23+/-0.04 kJ/min); by day 14, postprandial TEE was still greater with the MCT diet, but not significantly so. No significant differences in the thermic effect of feeding were evident between diets.
CONCLUSIONS: Results from this longest controlled MCT feeding study to date suggest that short-term feeding of MCT-enriched diets increases TEE, but this effect could be transient with continued feeding.

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Year:  1999        PMID: 10232626     DOI: 10.1093/ajcn/69.5.883

Source DB:  PubMed          Journal:  Am J Clin Nutr        ISSN: 0002-9165            Impact factor:   7.045


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