| Literature DB >> 10229229 |
H L Robinson1, D C Montefiori, R P Johnson, K H Manson, M L Kalish, J D Lifson, T A Rizvi, S Lu, S L Hu, G P Mazzara, D L Panicali, J G Herndon, R Glickman, M A Candido, S L Lydy, M S Wyand, H M McClure.
Abstract
Eight different protocols were compared for their ability to raise protection against immunodeficiency virus challenges in rhesus macaques. The most promising containment of challenge infections was achieved by intradermal DNA priming followed by recombinant fowl pox virus booster immunizations. This containment did not require neutralizing antibody and was active for a series of challenges ending with a highly virulent virus with a primary isolate envelope heterologous to the immunizing strain.Entities:
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Year: 1999 PMID： 10229229 DOI： 10.1038/8406
Source DB: PubMed Journal: Nat Med ISSN： 1078-8956 Impact factor: 53.440