| Literature DB >> 11152527 |
S Cherpelis1, I Shrivastava, A Gettie, X Jin, D D Ho, S W Barnett, L Stamatatos.
Abstract
DNA immunization of macaques with the SF162DeltaV2 envelope elicited lymphoproliferative responses and potent neutralizing antibodies. The animals were depleted of their CD8(+) T lymphocytes and then challenged intravenously with SHIV162P4. Compared to unvaccinated animals, the vaccinated macaques had lower peak viremia levels, rapidly cleared plasma virus, and showed delayed seroconversion.Entities:
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Year: 2001 PMID: 11152527 PMCID: PMC114060 DOI: 10.1128/JVI.75.3.1547-1550.2001
Source DB: PubMed Journal: J Virol ISSN: 0022-538X Impact factor: 5.103