Literature DB >> 10225942

Mechanisms of internalization of Staphylococcus aureus by cultured human osteoblasts.

M Jevon1, C Guo, B Ma, N Mordan, S P Nair, M Harris, B Henderson, G Bentley, S Meghji.   

Abstract

Staphylococcus aureus is an important bone pathogen, and evidence shows that this organism is internalized by chick osteoblasts. Here we report that S. aureus is internalized by human osteoblasts. Internalization was inhibited by monodansylcadaverine and cytochalasin D and to a lesser extent by ouabain, monensin, colchicine, and nocodazole. We propose that internalization occurs via a receptor-mediated pathway, requiring the participation of cytoskeletal elements, principally actin.

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Year:  1999        PMID: 10225942      PMCID: PMC116025     

Source DB:  PubMed          Journal:  Infect Immun        ISSN: 0019-9567            Impact factor:   3.441


  31 in total

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Journal:  Curr Opin Rheumatol       Date:  1991-08       Impact factor: 5.006

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Journal:  Nature       Date:  1980-01-10       Impact factor: 49.962

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Journal:  N Engl J Med       Date:  1985-03-21       Impact factor: 91.245

5.  Internalization of Staphylococcus aureus by endothelial cells induces apoptosis.

Authors:  B E Menzies; I Kourteva
Journal:  Infect Immun       Date:  1998-12       Impact factor: 3.441

6.  Depletion of intracellular potassium arrests coated pit formation and receptor-mediated endocytosis in fibroblasts.

Authors:  J M Larkin; M S Brown; J L Goldstein; R G Anderson
Journal:  Cell       Date:  1983-05       Impact factor: 41.582

Review 7.  Effects of exogenous amines on mammalian cells, with particular reference to membrane flow.

Authors:  R T Dean; W Jessup; C R Roberts
Journal:  Biochem J       Date:  1984-01-01       Impact factor: 3.857

8.  Monensin interrupts the recycling of low density lipoprotein receptors in human fibroblasts.

Authors:  S K Basu; J L Goldstein; R G Anderson; M S Brown
Journal:  Cell       Date:  1981-05       Impact factor: 41.582

9.  Actin microfilaments play a critical role in endocytosis at the apical but not the basolateral surface of polarized epithelial cells.

Authors:  T A Gottlieb; I E Ivanov; M Adesnik; D D Sabatini
Journal:  J Cell Biol       Date:  1993-02       Impact factor: 10.539

10.  Recycling of the asialoglycoprotein receptor and the effect of lysosomotropic amines in hepatoma cells.

Authors:  A L Schwartz; A Bolognesi; S E Fridovich
Journal:  J Cell Biol       Date:  1984-02       Impact factor: 10.539

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  55 in total

Review 1.  Osteoblast responses to bacterial pathogens: a previously unappreciated role for bone-forming cells in host defense and disease progression.

Authors:  Ian Marriott
Journal:  Immunol Res       Date:  2004       Impact factor: 2.829

2.  Induction of Nod1 and Nod2 intracellular pattern recognition receptors in murine osteoblasts following bacterial challenge.

Authors:  Ian Marriott; Dana M Rati; Samuel H McCall; Susanne L Tranguch
Journal:  Infect Immun       Date:  2005-05       Impact factor: 3.441

3.  Intra-cellular Staphylococcus aureus alone causes infection in vivo.

Authors:  T Hamza; M Dietz; D Pham; N Clovis; S Danley; B Li
Journal:  Eur Cell Mater       Date:  2013-07-08       Impact factor: 3.942

4.  Differential induction of inflammatory cytokines and reactive oxygen species in murine peritoneal macrophages and resident fresh bone marrow cells by acute staphylococcus aureus infection: contribution of toll-like receptor 2 (TLR2).

Authors:  Ajeya Nandi; Somrita Dey; Julie Biswas; Pooja Jaiswal; Shamreen Naaz; Tamima Yasmin; Biswadev Bishayi
Journal:  Inflammation       Date:  2015-02       Impact factor: 4.092

Review 5.  Taming the Triskelion: Bacterial Manipulation of Clathrin.

Authors:  Eleanor A Latomanski; Hayley J Newton
Journal:  Microbiol Mol Biol Rev       Date:  2019-02-27       Impact factor: 11.056

6.  Toll-Like Receptor 2 and Lipoprotein-Like Lipoproteins Enhance Staphylococcus aureus Invasion in Epithelial Cells.

Authors:  Minh-Thu Nguyen; Loulou Peisl; Francesca Barletta; Arif Luqman; Friedrich Götz
Journal:  Infect Immun       Date:  2018-07-23       Impact factor: 3.441

7.  Survival of Staphylococcus epidermidis in Fibroblasts and Osteoblasts.

Authors:  Kimberly Perez; Robin Patel
Journal:  Infect Immun       Date:  2018-09-21       Impact factor: 3.441

8.  Simultaneous bactericidal and osteogenic effect of nanoparticulate calcium phosphate powders loaded with clindamycin on osteoblasts infected with Staphylococcus aureus.

Authors:  Vuk Uskoković; Tejal A Desai
Journal:  Mater Sci Eng C Mater Biol Appl       Date:  2014-01-10       Impact factor: 7.328

Review 9.  Interaction of staphylococci with bone.

Authors:  John A Wright; Sean P Nair
Journal:  Int J Med Microbiol       Date:  2009-11-03       Impact factor: 3.473

Review 10.  Penetration of antibacterials into bone: pharmacokinetic, pharmacodynamic and bioanalytical considerations.

Authors:  Cornelia B Landersdorfer; Jürgen B Bulitta; Martina Kinzig; Ulrike Holzgrabe; Fritz Sörgel
Journal:  Clin Pharmacokinet       Date:  2009       Impact factor: 6.447

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