Literature DB >> 10224035

Elevated growth of Saccharomyces cerevisiae ATH1 null mutants on glucose is an artifact of nonmatching auxotrophies of mutant and reference strains.

R Chopra1, V M Sharma, K Ganesan.   

Abstract

Yeast strains disrupted for ATH1, which encodes vacuolar acid trehalase, have been reported to grow to higher cell densities than reference strains. We showed that the increase in cell density is due to the URA3 gene introduced as a part of the disruption and concluded that the misinterpretation is a result of not using a control strain with matching auxotrophic markers.

Entities:  

Mesh：

Substances：

Year:  1999        PMID： 10224035      PMCID： PMC91332     

Source DB:  PubMed          Journal:  Appl Environ Microbiol        ISSN： 0099-2240            Impact factor:   4.792


  9 in total

1.  Isolation and characterization of a novel yeast gene, ATH1, that is required for vacuolar acid trehalase activity.

Authors:  M Destruelle; H Holzer; D J Klionsky
Journal:  Yeast       Date:  1995-09-15       Impact factor: 3.239

2.  A network approach to the systematic analysis of yeast gene function.

Authors:  S Oliver
Journal:  Trends Genet       Date:  1996-07       Impact factor: 11.639

Review 3.  Pyruvate metabolism in Saccharomyces cerevisiae.

Authors:  J T Pronk; H Yde Steensma; J P Van Dijken
Journal:  Yeast       Date:  1996-12       Impact factor: 3.239

4.  Deletion of the ATH1 gene in Saccharomyces cerevisiae prevents growth on trehalose.

Authors:  S Nwaka; B Mechler; H Holzer
Journal:  FEBS Lett       Date:  1996-05-20       Impact factor: 4.124

5.  Osmostress-induced changes in yeast gene expression.

Authors:  J C Varela; C van Beekvelt; R J Planta; W H Mager
Journal:  Mol Microbiol       Date:  1992-08       Impact factor: 3.501

6.  Construction of a set of convenient Saccharomyces cerevisiae strains that are isogenic to S288C.

Authors:  F Winston; C Dollard; S L Ricupero-Hovasse
Journal:  Yeast       Date:  1995-01       Impact factor: 3.239

7.  Endocytosis and degradation of the yeast uracil permease under adverse conditions.

Authors:  C Volland; D Urban-Grimal; G Géraud; R Haguenauer-Tsapis
Journal:  J Biol Chem       Date:  1994-04-01       Impact factor: 5.157

8.  Disruption of the yeast ATH1 gene confers better survival after dehydration, freezing, and ethanol shock: potential commercial applications.

Authors:  J Kim; P Alizadeh; T Harding; A Hefner-Gravink; D J Klionsky
Journal:  Appl Environ Microbiol       Date:  1996-05       Impact factor: 4.792

9.  New heterologous modules for classical or PCR-based gene disruptions in Saccharomyces cerevisiae.

Authors:  A Wach; A Brachat; R Pöhlmann; P Philippsen
Journal:  Yeast       Date:  1994-12       Impact factor: 3.239
  9 in total
  8 in total

Review 1.  Auxotrophic yeast strains in fundamental and applied research.

Authors:  Jack T Pronk
Journal:  Appl Environ Microbiol       Date:  2002-05       Impact factor: 4.792

2.  Survival strategies of yeast and filamentous fungi against the antifungal protein AFP.

Authors:  Jean Paul Ouedraogo; Silke Hagen; Anja Spielvogel; Susanne Engelhardt; Vera Meyer
Journal:  J Biol Chem       Date:  2011-02-22       Impact factor: 5.157

3.  Regulation of the feruloyl esterase (faeA) gene from Aspergillus niger.

Authors:  R P de Vries; J Visser
Journal:  Appl Environ Microbiol       Date:  1999-12       Impact factor: 4.792

Review 4.  Osmotic stress signaling and osmoadaptation in yeasts.

Authors:  Stefan Hohmann
Journal:  Microbiol Mol Biol Rev       Date:  2002-06       Impact factor: 11.056

5.  System-level analysis of genes and functions affecting survival during nutrient starvation in Saccharomyces cerevisiae.

Authors:  David Gresham; Viktor M Boer; Amy Caudy; Naomi Ziv; Nathan J Brandt; John D Storey; David Botstein
Journal:  Genetics       Date:  2010-10-13       Impact factor: 4.562

6.  Saccharomyces cerevisiae Ats1p interacts with Nap1p, a cytoplasmic protein that controls bud morphogenesis.

Authors:  Christina M Shields; Rachel Taylor; Tara Nazarenus; Joseph Cheatle; Ann Hou; Audrey Tapprich; Alexis Haifley; Audrey L Atkin
Journal:  Curr Genet       Date:  2003-09-13       Impact factor: 3.886

7.  Self-cloning baker's yeasts that accumulate proline enhance freeze tolerance in doughs.

Authors:  Tomohiro Kaino; Tetsuya Tateiwa; Satomi Mizukami-Murata; Jun Shima; Hiroshi Takagi
Journal:  Appl Environ Microbiol       Date:  2008-07-18       Impact factor: 4.792

8.  Role of cultivation media in the development of yeast strains for large scale industrial use.

Authors:  Bärbel Hahn-Hägerdal; Kaisa Karhumaa; Christer U Larsson; Marie Gorwa-Grauslund; Johann Görgens; Willem H van Zyl
Journal:  Microb Cell Fact       Date:  2005-11-10       Impact factor: 5.328
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.