Literature DB >> 10223526

Treatment of tear of the anterior cruciate ligament combined with localised deep cartilage defects in the knee with ligament reconstruction and autologous periosteum transplantation.

H Alfredson1, K Thorsen, R Lorentzon.   

Abstract

An acute tear of the anterior cruciate ligament (ACL) is frequently associated with injuries to the joint cartilage and subchondral bone. These injuries may progress to deep cartilage defects, causing disabling pain, and represent a therapeutic challenge in patients with the combination instability and pain. At our clinic we treat patients with the combined injury with simultaneous ACL reconstruction and autologous periosteum transplantation of the cartilage defect. This report describes the technique for periosteum transplantation of full-thickness cartilage defects in the medial femoral condyle. Our clinical report includes the first 7 patients (6 men and 1 woman, mean age 29.1 years at operation) who have been followed for 2 years or longer of 14 consecutive patients (12 men and 2 women). All patients had suffered a total tear of the ACL and a full-thickness defect of the cartilage at the medial femoral condyle. The cartilage defects had a mean area of 7.3 cm2 (range 1.0-13.5 cm2). All patients had disabling instability and medial knee pain when walking. The anterior cruciate ligament was reconstructed with a bone-tendon-bone graft of the central third of the patellar ligament. After preparation of the cartilage lesion, the periosteum transplant was anchored to the underlying bone with suture anchors and fibrin glue. Postoperatively, these patients (n = 7) were initially treated with continuous passive motion, followed by active flexibility training and slowly progressing strength training and weight-bearing activities. At follow-up a mean of 31.3 months (range 24-38 months) later, 6 patients evidenced subjectively stable knees, no pain during rest or when walking, and had returned to not too heavy knee-loading work. One patient had a subjectively stable knee, but felt medial knee pain. Meticulous surgical technique and rigorous postoperative rehabilitation are probably of the greatest importance in this procedure. With the use of suture anchors and fibrin glue, the periosteum transplant can be well adapted to the condylar subchondral bone bed.

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Year:  1999        PMID: 10223526     DOI: 10.1007/s001670050124

Source DB:  PubMed          Journal:  Knee Surg Sports Traumatol Arthrosc        ISSN: 0942-2056            Impact factor:   4.342


  12 in total

1.  Treatment of full thickness chondral lesions of the knee with microfracture in a group of athletes.

Authors:  Alberto Gobbi; Perrico Nunag; Konrad Malinowski
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2004-05-14       Impact factor: 4.342

2.  The use of autologous chondrocyte implantation following and combined with anterior cruciate ligament reconstruction.

Authors:  A A Amin; W Bartlett; C R Gooding; M Sood; J A Skinner; R W J Carrington; T W R Briggs; G Bentley
Journal:  Int Orthop       Date:  2005-12-01       Impact factor: 3.075

3.  No evidence for the most appropriate postoperative rehabilitation protocol following anterior cruciate ligament reconstruction with concomitant articular cartilage lesions: a systematic review.

Authors:  Ciaran Thrush; Tabitha J Porter; Brian M Devitt
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2018-03-06       Impact factor: 4.342

4.  Pretreatment of periosteum with TGF-beta1 in situ enhances the quality of osteochondral tissue regenerated from transplanted periosteal grafts in adult rabbits.

Authors:  A Olivos-Meza; J S Fitzsimmons; M E Casper; Q Chen; K-N An; T J Ruesink; S W O'Driscoll; G G Reinholz
Journal:  Osteoarthritis Cartilage       Date:  2010-07-13       Impact factor: 6.576

5.  Periosteal transplantation to the rabbit patella.

Authors:  Lisbeth Brax Olofsson; Olle Svensson; Ronny Lorentzon; Inger Lindström; Håkan Alfredson
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2006-10-28       Impact factor: 4.342

6.  Full-thickness cartilage lesion do not affect knee function in patients with ACL injury.

Authors:  Vegar Hjermundrud; Tonje Kvist Bjune; May Arna Risberg; Lars Engebretsen; Asbjørn Arøen
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2009-09-04       Impact factor: 4.342

7.  Rehabilitation after one-stage anterior cruciate reconstruction and osteochondral grafting.

Authors:  Krzysztof Gaweda; Jacek Walawski; Robert Wegłowski; Maciej Patyra
Journal:  Int Orthop       Date:  2006-03-18       Impact factor: 3.075

8.  Anterior cruciate reconstruction combined with autologous osteochondral transplantation.

Authors:  Hans-Michael Klinger; Mike H Baums; Stephanie Otte; Hanno Steckel
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2003-09-13       Impact factor: 4.342

9.  Rejuvenation of periosteal chondrogenesis using local growth factor injection.

Authors:  G G Reinholz; J S Fitzsimmons; M E Casper; T J Ruesink; H W Chung; J C Schagemann; S W O'Driscoll
Journal:  Osteoarthritis Cartilage       Date:  2008-11-06       Impact factor: 6.576

10.  The location-specific healing response of damaged articular cartilage after ACL reconstruction: short-term follow-up.

Authors:  Norimasa Nakamura; Shuji Horibe; Yukiyoshi Toritsuka; Tomoki Mitsuoka; Takashi Natsu-ume; Kenji Yoneda; Masayuki Hamada; Yoshinari Tanaka; Richard S Boorman; Hideki Yoshikawa; Konsei Shino
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2008-06-13       Impact factor: 4.342

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