Literature DB >> 10217726

Stereoselective total synthesis of (3R,8S)-falcarindiol, a common polyacetylenic compound from umbellifers

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Abstract

The first stereoselective total synthesis of (3R,8S)-falcarindiol (1) from L-tartaric acid and D-xylose is reported, via the Cadiot-Chodkiczwicz reaction, to couple 1-bromoalkyne (2) with 3(R)-(tert-butyldiphenylsilyloxy)-1-penten-4-yne (3).

Entities:  

Year:  1999        PMID： 10217726     DOI： 10.1021/np980418z

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  4 in total

1.  Serotonergic activity-guided phytochemical investigation of the roots of Angelica sinensis.

Authors:  Shixin Deng; Shao-Nong Chen; Ping Yao; Dejan Nikolic; Richard B van Breemen; Judy L Bolton; Harry H S Fong; Norman R Farnsworth; Guido F Pauli
Journal:  J Nat Prod       Date:  2006-04       Impact factor: 4.050

2.  Anti-TB polyynes from the roots of Angelica sinensis.

Authors:  Shixin Deng; Yuehong Wang; Taichi Inui; Shao-Nong Chen; Norman R Farnsworth; Sanghyun Cho; Scott G Franzblau; Guido F Pauli
Journal:  Phytother Res       Date:  2008-07       Impact factor: 5.878

Review 3.  Natural products possessing protein tyrosine phosphatase 1B (PTP1B) inhibitory activity found in the last decades.

Authors:  Cheng-Shi Jiang; Lin-fu Liang; Yue-wei Guo
Journal:  Acta Pharmacol Sin       Date:  2012-09-03       Impact factor: 6.150

4.  Isolation and identification of two new polyynes from a North American ethnic medicinal plant--Oplopanax horridus (Smith) Miq.

Authors:  Wei-Hua Huang; Qing-Wen Zhang; Chong-Zhi Wang; Chun-Su Yuan; Shao-Ping Li
Journal:  Molecules       Date:  2010-02-23       Impact factor: 4.411
  4 in total

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