Literature DB >> 102111

Thyrotropin-releasing factor: distribution in neural and gastrointestinal tissues.

J Leppäluoto, F Koivusalo, R Kraama.   

Abstract

Specimens of several rat tissues were purified with methanol extraction, gel filtration and cation exchange chromatography and measured for thyrotropin-releasing factor (TRF) concentration by radioimmunoassay. TRF immunoreactivity of neural tissues (hypothalamus, spinal cord, medulla, cerebrum and cerebellum) and gastrointestinal tissues (pancreas, stomach, duodenum and colon) behaved as synthetic TRF during the purification. This dual distribution suggests that TRF-secreting cells have their origin in the embryonal neuroectoderm.

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Year:  1978        PMID： 102111     DOI： 10.1111/j.1748-1716.1978.tb06264.x

Source DB:  PubMed          Journal:  Acta Physiol Scand        ISSN： 0001-6772


  24 in total

1.  Ontogenesis of thyrotropin-releasing hormone in the human fetal pancreas. A combined radioimmunological and immunocytochemical study.

Authors:  P Leduque; S Aratan-Spire; P Czernichow; P M Dubois
Journal:  J Clin Invest       Date:  1986-10       Impact factor: 14.808

2.  Abnormal neuropeptide concentration in rectal mucosa of patients with inflammatory bowel disease.

Authors:  H Yamamoto; K Morise; K Kusugami; A Furusawa; T Konagaya; Y Nishio; H Kaneko; K Uchida; H Nagai; T Mitsuma; H Nagura
Journal:  J Gastroenterol       Date:  1996-08       Impact factor: 7.527

3.  Plasma levels of thyrotropin-releasing-hormone in various splanchnic, renal, suprarenal, and cerebral veins.

Authors:  I Vardarl; J M Wdowinski; J Hoevels; R Schmidt; U Schwedes; M Georgi; K H Usadel
Journal:  Klin Wochenschr       Date:  1987-02-02

4.  Effect of low intravenous doses of TRH, acid-TRH and cyclo(His-Pro) on cerebral and peripheral blood flows.

Authors:  L O Koskinen
Journal:  Br J Pharmacol       Date:  1986-03       Impact factor: 8.739

5.  Evidence for pyroglutamyl peptidase I and prolyl endopeptidase activities in the rat insulinoma cell line RINm 5F: lack of relationship with TRH metabolism.

Authors:  P Salers; L H Ouafik; P Giraud; A Dutour; J Y Maltese; C Oliver
Journal:  Mol Cell Biochem       Date:  1991-07-24       Impact factor: 3.396

6.  Ontogenetic patterns of thyrotropin-releasing hormone-like material in rat hypothalamus, pancreas, and retina: selective effect of light deprivation.

Authors:  E Martino; H Seo; A Lernmark; S Refetoff
Journal:  Proc Natl Acad Sci U S A       Date:  1980-07       Impact factor: 11.205

7.  Effects of NG-nitro-L-arginine methyl ester on the cardiovascular system of the anaesthetized rabbit and on the cardiovascular response to thyrotropin-releasing hormone.

Authors:  E E Seligsohn; A Bill
Journal:  Br J Pharmacol       Date:  1993-08       Impact factor: 8.739

8.  The role of thyrotropin-releasing hormone (TRH) in the pathogenesis of water-immersion stress in rats--inhibition of TRH release from the stomach by atropine, ranitidine or omeprazole.

Authors:  K Uchida; T Mitsuma; K Morise; H Kaneko; H Nagai; A Furusawa; K Nakada; Y Maeda
Journal:  Gastroenterol Jpn       Date:  1993-02

9.  Role of thyrotropin-releasing hormone in stress ulcer formation in the rat.

Authors:  N Basso; M Bagarani; A E Pekary; A Genco; A Materia
Journal:  Dig Dis Sci       Date:  1988-07       Impact factor: 3.199

10.  TRH-like immunoreactivity in endocrine cells and neurons in the gastro-intestinal tract of the rat and guinea pig.

Authors:  Y Tsuruo; T Hökfelt; T J Visser; J R Kimmel; J C Brown; A Verhofstadt; J Walsh
Journal:  Cell Tissue Res       Date:  1988-08       Impact factor: 5.249
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