Literature DB >> 10209155

Multiple positive and negative regulators of signaling by the EGF-receptor.

N Moghal1, P W Sternberg.   

Abstract

Signaling via the epidermal growth factor (EGF)-receptor family is subject to regulation and modulation by multiple ligands, effectors and negative regulators, as well as regulation by heterodimerization between family members and crosstalk between heterologous signaling pathways. Besides serving as a paradigm for receptor tyrosine kinases in general, this family is crucial for development and is often mutated or amplified in human tumors.

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Year:  1999        PMID： 10209155     DOI： 10.1016/s0955-0674(99)80025-8

Source DB:  PubMed          Journal:  Curr Opin Cell Biol        ISSN： 0955-0674            Impact factor:   8.382


  57 in total

1.  Phosphorylation of the PTEN tail regulates protein stability and function.

Authors:  F Vazquez; S Ramaswamy; N Nakamura; W R Sellers
Journal:  Mol Cell Biol       Date:  2000-07       Impact factor: 4.272

Review 2.  ErbB-4: a receptor tyrosine kinase.

Authors:  W Zhou; G Carpenter
Journal:  Inflamm Res       Date:  2002-02       Impact factor: 4.575

3.  The bimodal regulation of epidermal growth factor signaling by human Sprouty proteins.

Authors:  James E Egan; Amy B Hall; Bogdan A Yatsula; Dafna Bar-Sagi
Journal:  Proc Natl Acad Sci U S A       Date:  2002-04-30       Impact factor: 11.205

4.  Spatial range of autocrine signaling: modeling and computational analysis.

Authors:  S Y Shvartsman; H S Wiley; W M Deen; D A Lauffenburger
Journal:  Biophys J       Date:  2001-10       Impact factor: 4.033

5.  Amphiregulin promotes intestinal epithelial regeneration: roles of intestinal subepithelial myofibroblasts.

Authors:  Jinyi Shao; Hongmiao Sheng
Journal:  Endocrinology       Date:  2010-06-09       Impact factor: 4.736

6.  Long-range signal transmission in autocrine relays.

Authors:  Michal Pribyl; Cyrill B Muratov; Stanislav Y Shvartsman
Journal:  Biophys J       Date:  2003-02       Impact factor: 4.033

7.  Neuronal Cbl controls biosynthesis of insulin-like peptides in Drosophila melanogaster.

Authors:  Yue Yu; Ying Sun; Shengqi He; Cheng Yan; Liangyou Rui; Wenjun Li; Yong Liu
Journal:  Mol Cell Biol       Date:  2012-07-09       Impact factor: 4.272

8.  Sprouty2 attenuates epidermal growth factor receptor ubiquitylation and endocytosis, and consequently enhances Ras/ERK signalling.

Authors:  Esther Sook Miin Wong; Chee Wai Fong; Jormay Lim; Permeen Yusoff; Boon Chuan Low; Wallace Y Langdon; Graeme R Guy
Journal:  EMBO J       Date:  2002-09-16       Impact factor: 11.598

9.  Phosphatidylinositol 3-kinase mediates proliferative signals in intestinal epithelial cells.

Authors:  H Sheng; J Shao; C M Townsend; B M Evers
Journal:  Gut       Date:  2003-10       Impact factor: 23.059

10.  A conserved mechanism for extracellular signaling in eukaryotes and prokaryotes.

Authors:  Marco Gallio; Gwen Sturgill; Philip Rather; Per Kylsten
Journal:  Proc Natl Acad Sci U S A       Date:  2002-09-09       Impact factor: 11.205
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