AIM: To study the epidemiology of childhood tuberculosis (TB) in a developing country. SETTING: Two urban communities of Cape Town, South Africa with a TB case notification rate of 1149/100 000. DESIGN: Retrospective descriptive study using the national population census (1991), 10 year official TB notification records, and a geographical information system. RESULTS: The case notification rate of TB in children 0-5 years old was 3588 cases/100 000 children aged 0-5 years, 3.5 times the case notification rate in adults. Children (0-14 years) accounted for 39% of the total case load. Childhood TB case notification rate correlated with parental education (r = -0.64), annual household income (r = -0.6), and crowding (r = 0.32). CONCLUSION: Children, especially those living in poor socioeconomic conditions, form an important epidemiological group and account for a notable proportion of the morbidity caused by TB. Efforts to improve TB control must therefore not only target adults (case detection and cure of infectious cases) but also children (screening of child contacts of adult cases) and the socioeconomic living conditions.
AIM: To study the epidemiology of childhood tuberculosis (TB) in a developing country. SETTING: Two urban communities of Cape Town, South Africa with a TB case notification rate of 1149/100 000. DESIGN: Retrospective descriptive study using the national population census (1991), 10 year official TB notification records, and a geographical information system. RESULTS: The case notification rate of TB in children 0-5 years old was 3588 cases/100 000 children aged 0-5 years, 3.5 times the case notification rate in adults. Children (0-14 years) accounted for 39% of the total case load. Childhood TB case notification rate correlated with parental education (r = -0.64), annual household income (r = -0.6), and crowding (r = 0.32). CONCLUSION:Children, especially those living in poor socioeconomic conditions, form an important epidemiological group and account for a notable proportion of the morbidity caused by TB. Efforts to improve TB control must therefore not only target adults (case detection and cure of infectious cases) but also children (screening of child contacts of adult cases) and the socioeconomic living conditions.
Authors: S Ade; A D Harries; A Trébucq; S G Hinderaker; G Ade; G Agodokpessi; D Affolabi; S Koumakpaï; S Anagonou; M Gninafon Journal: Public Health Action Date: 2013-03-21
Authors: L M van Leeuwen; P Versteegen; S D Zaharie; S L van Elsland; A Jordaan; E M Streicher; R M Warren; M van der Kuip; A M van Furth Journal: J Clin Microbiol Date: 2019-07-26 Impact factor: 5.948
Authors: A D Harries; S M Graham; M M Weismuller; Njm Claessens; S Meijnen; N J Hargreaves; C Mwansambo; P N Kazembe; F M Salaniponi Journal: Malawi Med J Date: 2005-12 Impact factor: 0.875
Authors: Alison M Elliott; Moses Kizza; Maria A Quigley; Juliet Ndibazza; Margaret Nampijja; Lawrence Muhangi; Linda Morison; Proscovia B Namujju; Moses Muwanga; Narcis Kabatereine; James A G Whitworth Journal: Clin Trials Date: 2007 Impact factor: 2.486
Authors: Shobana Rebecca Dissanayeke; Samuel Levin; Sandra Pienaar; Kathryn Wood; Brian Eley; David Beatty; Howard Henderson; Suzanne Anderson; Michael Levin Journal: PLoS One Date: 2009-08-20 Impact factor: 3.240