Literature DB >> 10204276

Symptom structure in obsessive-compulsive disorder: a confirmatory factor-analytic study.

L J Summerfeldt1, M A Richter, M M Antony, R P Swinson.   

Abstract

Although obsessive-compulsive disorder (OCD) has long been a unitary diagnosis, there is much recent interest in its potential heterogeneity, as manifested by symptom subgroups. This study evaluated existing models of symptom structure in a sample of 203 individuals with OCD. Using confirmatory factor analysis, we examined the ability of each model to account for two levels of data: a priori symptom groupings (second-order) and individual symptoms, identified by the Yale-Brown Obsessive Compulsive Scale symptom checklist. Four models were examined: a single-factor, a two-factor (i.e., obsessions and compulsions), and two multidimensional models, comprising three and four factors. Adequate fit was found solely for the four-factor model--specifying obsessions/checking, symmetry/ordering, contamination/cleaning, and hoarding--but only at the second-order level; it did not account for relationships among discrete symptoms. Parameter estimates showed within-factor heterogeneity, as well as overlap between factors, most notably the two representing checking and contamination-related symptoms. The implications of these findings are discussed. Results provide evidence for the multidimensionality of OCD symptoms, but suggest that a comprehensive model has yet to be identified. They also point to the inadequacy of groupings based solely upon overt behavioural similarities (e.g., 'checking'). Recommendations are made for future research.

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Year:  1999        PMID: 10204276     DOI: 10.1016/s0005-7967(98)00134-x

Source DB:  PubMed          Journal:  Behav Res Ther        ISSN: 0005-7967


  32 in total

1.  Evidence for cortical inhibitory and excitatory dysfunction in obsessive compulsive disorder.

Authors:  Margaret A Richter; Danilo R de Jesus; Sylco Hoppenbrouwers; Melissa Daigle; Jasna Deluce; Lakshmi N Ravindran; Paul B Fitzgerald; Zafiris J Daskalakis
Journal:  Neuropsychopharmacology       Date:  2011-12-14       Impact factor: 7.853

2.  Paroxetine treatment of compulsive hoarding.

Authors:  Sanjaya Saxena; Arthur L Brody; Karron M Maidment; Lewis R Baxter
Journal:  J Psychiatr Res       Date:  2006-06-21       Impact factor: 4.791

3.  Genomewide scan of hoarding in sib pairs in which both sibs have Gilles de la Tourette syndrome.

Authors:  Heping Zhang; James F Leckman; David L Pauls; Chin-Pei Tsai; Kenneth K Kidd; M Rosario Campos
Journal:  Am J Hum Genet       Date:  2002-02-11       Impact factor: 11.025

Review 4.  Translational approaches to obsessive-compulsive disorder: from animal models to clinical treatment.

Authors:  N A Fineberg; S R Chamberlain; E Hollander; V Boulougouris; T W Robbins
Journal:  Br J Pharmacol       Date:  2011-10       Impact factor: 8.739

Review 5.  Obsessive-compulsive disorder: a review of the diagnostic criteria and possible subtypes and dimensional specifiers for DSM-V.

Authors:  James F Leckman; Damiaan Denys; H Blair Simpson; David Mataix-Cols; Eric Hollander; Sanjaya Saxena; Euripedes C Miguel; Scott L Rauch; Wayne K Goodman; Katharine A Phillips; Dan J Stein
Journal:  Depress Anxiety       Date:  2010-06       Impact factor: 6.505

6.  Validation of the Turkish Version of the Obsessive-Compulsive Inventory-Revised (OCI-R) in Clinical and Non-Clinical Samples.

Authors:  Adem Aydin; Murat Boysan; Temel Kalafat; Yavuz Selvi; Lütfullah Beşiroğlu; Mücahit Kagan
Journal:  Noro Psikiyatr Ars       Date:  2014-03-01       Impact factor: 1.339

7.  Dissociative Experiences are Associated with Obsessive-Compulsive Symptoms in a Non-clinical Sample: A Latent Profile Analysis.

Authors:  Murat Boysan
Journal:  Noro Psikiyatr Ars       Date:  2014-09-01       Impact factor: 1.339

8.  Dimensional predictors of response to SRI pharmacotherapy in obsessive-compulsive disorder.

Authors:  Angeli Landeros-Weisenberger; Michael H Bloch; Ben Kelmendi; Ryan Wegner; Jake Nudel; Philip Dombrowski; Christopher Pittenger; John H Krystal; Wayne K Goodman; James F Leckman; Vladimir Coric
Journal:  J Affect Disord       Date:  2009-07-03       Impact factor: 4.839

9.  Psychometric properties of the DY-BOCS in a Turkish sample of children and adolescents.

Authors:  Ayşegül Selcen Güler; Maria Conceição do Rosário; Ayşe Burcu Ayaz; Sebla Gökçe; Yasemin Yulaf; Senem Başgül; Özlem Özcan; Koray Karabekiroğlu; Kerim Munir; Lütfullah Beşiroğlu; Yankı Yazgan
Journal:  Compr Psychiatry       Date:  2015-09-24       Impact factor: 3.735

10.  Autism and ADHD symptoms in patients with OCD: are they associated with specific OC symptom dimensions or OC symptom severity?

Authors:  Gideon E Anholt; Danielle C Cath; Patricia van Oppen; Merijn Eikelenboom; Johannes H Smit; Harold van Megen; Anton J L M van Balkom
Journal:  J Autism Dev Disord       Date:  2010-05
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