Literature DB >> 10196782

Effects of X-ray irradiation on genomic DNA methylation levels in mouse tissues.

R Tawa1, Y Kimura, J Komura, Y Miyamura, A Kurishita, M S Sasaki, H Sakurai, T Ono.   

Abstract

Effects of ionizing radiation on the level of genomic DNA methylation in liver, brain and spleen of mouse as well as in two kinds of cultured cells were examined by high-performance liquid chromatography. Ten Gy of whole body X-radiation reduced the 5-methyldeoxycytidine contents by about 40% within 8 hours after irradiation in liver. Similar effects were observed at 4 or 7 Gy of X-ray irradiation. However, no such change was detected in brain, spleen and cultured cells. The data indicate that radiation-induced alteration in genomic DNA methylation is not ubiquitous among different tissues and cells.

Entities:  

Mesh：

Year:  1998        PMID： 10196782     DOI： 10.1269/jrr.39.271

Source DB:  PubMed          Journal:  J Radiat Res        ISSN： 0449-3060            Impact factor:   2.724


  24 in total

1.  Sensitive quantitative analysis of murine LINE1 DNA methylation using high resolution melt analysis.

Authors:  Michelle Newman; Benjamin J Blyth; Damian J Hussey; Daniel Jardine; Pamela J Sykes; Rebecca J Ormsby
Journal:  Epigenetics       Date:  2012-01-01       Impact factor: 4.528

2.  Adaptive radiation-induced epigenetic alterations mitigated by antioxidants.

Authors:  Autumn J Bernal; Dana C Dolinoy; Dale Huang; David A Skaar; Caren Weinhouse; Randy L Jirtle
Journal:  FASEB J       Date:  2012-11-01       Impact factor: 5.191

Review 3.  Effects of ionizing radiation on DNA methylation: from experimental biology to clinical applications.

Authors:  Isabelle R Miousse; Kristy R Kutanzi; Igor Koturbash
Journal:  Int J Radiat Biol       Date:  2017-02-21       Impact factor: 2.694

Review 4.  Response of transposable elements to environmental stressors.

Authors:  Isabelle R Miousse; Marie-Cecile G Chalbot; Annie Lumen; Alesia Ferguson; Ilias G Kavouras; Igor Koturbash
Journal:  Mutat Res Rev Mutat Res       Date:  2015-05-30       Impact factor: 5.657

Review 5.  Radiotherapy role in non-seminomatous germ cell tumors, radiobiological and technical issues of an unexplored scenario.

Authors:  Giulio Francolini; Luca Eolo Trodella; Giulia Marvaso; Fabio Matrone; Luca Nicosia; Giorgia Timon; Lucia Ognibene; Annamaria Vinciguerra; Ciro Franzese; Paolo Borghetti; Stefano Arcangeli
Journal:  Int J Clin Oncol       Date:  2021-07-17       Impact factor: 3.402

6.  2017 Michael Fry Award Lecture When DNA is Actually Not a Target: Radiation Epigenetics as a Tool to Understand and Control Cellular Response to Ionizing Radiation.

Authors:  Igor Koturbash
Journal:  Radiat Res       Date:  2018-04-26       Impact factor: 2.841

Review 7.  Heavy ions, radioprotectors and genomic instability: implications for human space exploration.

Authors:  Jaroslaw Dziegielewski; Wilfried Goetz; Janet E Baulch
Journal:  Radiat Environ Biophys       Date:  2009-12-25       Impact factor: 1.925

8.  The epigenetic and morphogenetic effects of molecular oxygen and its derived reactive species in development.

Authors:  Michael J Hitchler; Frederick E Domann
Journal:  Free Radic Biol Med       Date:  2021-01-12       Impact factor: 8.101

9.  A single whole-body low dose X-irradiation does not affect L1, B1 and IAP repeat element DNA methylation longitudinally.

Authors:  Michelle R Newman; Pamela J Sykes; Benjamin J Blyth; Eva Bezak; Mark D Lawrence; Katherine L Morel; Rebecca J Ormsby
Journal:  PLoS One       Date:  2014-03-27       Impact factor: 3.240

10.  Axin gene methylation status correlates with radiosensitivity of lung cancer cells.

Authors:  Lian-He Yang; Yang Han; Guang Li; Hong-Tao Xu; Gui-Yang Jiang; Yuan Miao; Xiu-Peng Zhang; Huan-Yu Zhao; Zheng-Fan Xu; Maggie Stoecker; Endi Wang; Ke Xu; En-Hua Wang
Journal:  BMC Cancer       Date:  2013-08-02       Impact factor: 4.430
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