Literature DB >> 10189718

Powerful tools for genetic analysis come of age.

D J Graves1.   

Abstract

Microscopic arrays of oligonucleotides or cDNA containing up to several hundred thousand different sequences are starting to influence methodologies and paths to discovery in genomics. Gene polymorphisms and mutations can be found and gene expression measured with unprecedented speed and parallelism. The principles of this modern technology and some of the problems awaiting further study are discussed.

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Year:  1999        PMID： 10189718     DOI： 10.1016/s0167-7799(98)01241-4

Source DB:  PubMed          Journal:  Trends Biotechnol        ISSN： 0167-7799            Impact factor:   19.536


  15 in total

Review 1.  The impact of molecular medicine upon early cardiovascular drug development.

Authors:  M W Lunnon; M Braddock
Journal:  Br J Clin Pharmacol       Date:  2000-07       Impact factor: 4.335

2.  An assessment of Motorola CodeLink microarray performance for gene expression profiling applications.

Authors:  Ramesh Ramakrishnan; David Dorris; Anna Lublinsky; Allen Nguyen; Marc Domanus; Anna Prokhorova; Linn Gieser; Edward Touma; Randall Lockner; Murthy Tata; Xiaomei Zhu; Marcus Patterson; Richard Shippy; Timothy J Sendera; Abhijit Mazumder
Journal:  Nucleic Acids Res       Date:  2002-04-01       Impact factor: 16.971

3.  Sensitivity, specificity, and the hybridization isotherms of DNA chips.

Authors:  A Halperin; A Buhot; E B Zhulina
Journal:  Biophys J       Date:  2004-02       Impact factor: 4.033

4.  Competitive hybridization kinetics reveals unexpected behavior patterns.

Authors:  Ying Zhang; Daniel A Hammer; David J Graves
Journal:  Biophys J       Date:  2005-08-26       Impact factor: 4.033

5.  Brush effects on DNA chips: thermodynamics, kinetics, and design guidelines.

Authors:  A Halperin; A Buhot; E B Zhulina
Journal:  Biophys J       Date:  2005-05-20       Impact factor: 4.033

6.  Modeling Effects of Surface Properties and Probe Density for Nanoscale Biosensor Design: A Case Study of DNA Hybridization near Surfaces.

Authors:  Timothy Cholko; Chia-En A Chang
Journal:  J Phys Chem B       Date:  2021-02-16       Impact factor: 2.991

7.  Introduction to project MIDTAL: its methods and samples from Arcachon Bay, France.

Authors:  Jessica U Kegel; Yolanda Del Amo; Linda K Medlin
Journal:  Environ Sci Pollut Res Int       Date:  2012-11-22       Impact factor: 4.223

8.  Use of a suspension array for rapid identification of the varieties and genotypes of the Cryptococcus neoformans species complex.

Authors:  Mara R Diaz; Jack W Fell
Journal:  J Clin Microbiol       Date:  2005-08       Impact factor: 5.948

Review 9.  Real-time DNA microarrays: reality check.

Authors:  Alexander Chagovetz; Steve Blair
Journal:  Biochem Soc Trans       Date:  2009-04       Impact factor: 5.407

10.  DNA surface hybridization regimes.

Authors:  Ping Gong; Rastislav Levicky
Journal:  Proc Natl Acad Sci U S A       Date:  2008-04-01       Impact factor: 11.205
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