Literature DB >> 10171203

Injection moulding of biodegradable implants.

R von Oepen1, W Michaeli.   

Abstract

In medical engineering, degradable polymers represent an attractive alternative for conventional materials to be used as implants in the body. They are used as drug deliveries or as plates and screws to fix broken bones. Since they are completely broken down by the human body, the second operation, which is generally required, can be avoided. A central problem is the processing of these polymers, because no stabilisers are allowed. This causes a partially relevant loss in molecular weight, which correlates directly with the mechanical properties. Tests carried out on an injection moulding machine and on a conical plate rheometer show the influence of temperature, shear, residence time and moisture on molecular weight reduction and mechanical properties.

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Year:  1992        PMID: 10171203     DOI: 10.1016/0267-6605(92)90080-d

Source DB:  PubMed          Journal:  Clin Mater        ISSN: 0267-6605


  7 in total

Review 1.  Biomaterials in orthopaedics.

Authors:  M Navarro; A Michiardi; O Castaño; J A Planell
Journal:  J R Soc Interface       Date:  2008-10-06       Impact factor: 4.118

2.  A new resorbable device for ligation of blood vessels - A pilot study.

Authors:  Odd V Höglund; Ragnvi Hagman; Kerstin Olsson; Jonas Mindemark; Niklas Borg; Anne-Sofie Lagerstedt
Journal:  Acta Vet Scand       Date:  2011-07-08       Impact factor: 1.695

3.  Tuning the compatibility to achieve toughened biobased poly(lactic acid)/poly(butylene terephthalate) blends.

Authors:  Boon Peng Chang; Amar K Mohanty; Manjusri Misra
Journal:  RSC Adv       Date:  2018-08-03       Impact factor: 4.036

4.  Non-conventional injection molding of poly(lactide) and poly(epsilon-caprolactone) intended for orthopedic applications.

Authors:  H Altpeter; M J Bevis; D W Grijpma; J Feijen
Journal:  J Mater Sci Mater Med       Date:  2004-02       Impact factor: 3.896

5.  Physical properties of high molecular weight 1,3-trimethylene carbonate and D,L-lactide copolymers.

Authors:  Ana Paula Pêgo; André A Poot; Dirk W Grijpma; Jan Feijen
Journal:  J Mater Sci Mater Med       Date:  2003-09       Impact factor: 3.896

6.  Degradative and mechanical properties of a novel resorbable plating system during a 3-year follow-up in vivo and in vitro.

Authors:  Tuomo Nieminen; Immo Rantala; Ilmari Hiidenheimo; Jaakko Keränen; Heikki Kainulainen; Erkki Wuolijoki; Ilkka Kallela
Journal:  J Mater Sci Mater Med       Date:  2007-08-15       Impact factor: 3.896

7.  Process-Property Relationships for Melt-Spun Poly(lactic acid) Yarn.

Authors:  Chirag R Gajjar; Jon W Stallrich; Melissa A Pasquinelli; Martin W King
Journal:  ACS Omega       Date:  2021-06-09
  7 in total

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