Literature DB >> 10146954

Discounting of health benefits in the pharmacoeconomic analysis of drug therapies: an issue for debate?

D Coyle1, K Tolley.   

Abstract

In most economic evaluations, future monetary costs and benefits and future health benefits are discounted at the same rate. The purpose of this article is to question such current practice. The primary reason behind discounting costs and benefits is to allow for individuals' preferences over the timing of such events, i.e. to represent social time preference. We argue that the social time preference rate for health benefits is unlikely to be the same as that for monetary costs and benefits. The results of a sensitivity analysis of pharmacoeconomic analyses of drug treatments for hypertension illustrate how the choice of discount rate can affect the conclusions. As no definite conclusions can be drawn regarding the magnitude of the discount rate for health benefits, we recommend that analysts conduct sensitivity analyses employing differential discount rates for health benefits as well as monetary costs and benefits.

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Year:  1992        PMID: 10146954     DOI: 10.2165/00019053-199202020-00007

Source DB:  PubMed          Journal:  Pharmacoeconomics        ISSN: 1170-7690            Impact factor:   4.981


  7 in total

1.  First principles of cost-effectiveness analysis in health.

Authors:  D S Shepard; M S Thompson
Journal:  Public Health Rep       Date:  1979 Nov-Dec       Impact factor: 2.792

2.  Discounting and health benefits.

Authors:  M Parsonage; H Neuburger
Journal:  Health Econ       Date:  1992-04       Impact factor: 3.046

3.  Discounting and health benefits: another perspective.

Authors:  J Cairns
Journal:  Health Econ       Date:  1992-04       Impact factor: 3.046

4.  Principles of pharmacoeconomic analysis of drug therapy.

Authors:  D A Freund; R S Dittus
Journal:  Pharmacoeconomics       Date:  1992-01       Impact factor: 4.981

Review 5.  Assessing the economic value of antihypertensive medicines.

Authors:  M Drummond; D Coyle
Journal:  J Hum Hypertens       Date:  1992-12       Impact factor: 3.012

6.  Foundations of cost-effectiveness analysis for health and medical practices.

Authors:  M C Weinstein; W B Stason
Journal:  N Engl J Med       Date:  1977-03-31       Impact factor: 91.245

7.  Estrogen use in postmenopausal women--costs, risks, and benefits.

Authors:  M C Weinstein
Journal:  N Engl J Med       Date:  1980-08-07       Impact factor: 91.245

  7 in total
  22 in total

Review 1.  Handling uncertainty in cost-effectiveness models.

Authors:  A H Briggs
Journal:  Pharmacoeconomics       Date:  2000-05       Impact factor: 4.981

Review 2.  Theoretical arguments for the discounting of health consequences: where do we go from here?

Authors:  Angelina Lazaro
Journal:  Pharmacoeconomics       Date:  2002       Impact factor: 4.981

3.  Discounting in cost-effectiveness analysis of healthcare programmes.

Authors:  D A Katz; H G Welch
Journal:  Pharmacoeconomics       Date:  1993-04       Impact factor: 4.981

4.  Time preference for health gains versus health losses.

Authors:  L D MacKeigan; L N Larson; J R Draugalis; J L Bootman; L R Burns
Journal:  Pharmacoeconomics       Date:  1993-05       Impact factor: 4.981

5.  Regulation of the pharmaceutical industry and now pharmacoeconomic research?

Authors:  N E Wells
Journal:  Pharmacoeconomics       Date:  1992-12       Impact factor: 4.981

6.  Cost-effectiveness analysis: obstacles to standardisation and its use in regulating pharmaceuticals.

Authors:  B R Luce
Journal:  Pharmacoeconomics       Date:  1993-01       Impact factor: 4.981

7.  QALY league tables revisited.

Authors:  C M Gudex
Journal:  Pharmacoeconomics       Date:  1993-05       Impact factor: 4.981

8.  The reliability of cost-utility estimates in cost-per-QALY league tables .

Authors:  S Petrou; M Malek; P G Davey
Journal:  Pharmacoeconomics       Date:  1993-05       Impact factor: 4.981

9.  Economic evaluation of pharmaceuticals: a critical appraisal of seven studies on cholesterol-lowering agents.

Authors:  P Gazzaniga; L Garattini
Journal:  Pharmacoeconomics       Date:  1992-10       Impact factor: 4.981

10.  An economic analysis of the Survival and Ventricular Enlargement (SAVE) Study. Application to the United Kingdom.

Authors:  S Hummel; J Piercy; R Wright; A Davie; A Bagust; J McMurray
Journal:  Pharmacoeconomics       Date:  1997-08       Impact factor: 4.981

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