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Literature DB >> 10103207

Protection by short-chain fatty acids against 1-beta-D-arabinofuranosylcytosine-induced intestinal lesions in germfree mice.

M G Ramos¹, E A Bambirra, J R Nicoli, D C Cara, E C Vieira, J Alvarez-Leite.

Abstract

In germfree mice, the administration of short-chain fatty acids (SCFA) protected the intestinal mucosa from damage produced by 1-beta-D-arabinofuranosylcytosine (Ara-C). Animals receiving SCFA and Ara-C had intestinal morphologies closer to normal than the control animals, which had severe intestinal lesions. We concluded that orally administrated SCFA reduce intestinal lesions, improving the mucosa pattern of the small intestine and colon.

Entities: Chemical Disease Species

Mesh：

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Year: 1999 PMID： 10103207 PMCID： PMC89233

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

10 in total

Review 1. Short-chain fatty acids in ulcerative colitis.

Authors: Y I Kim
Journal: Nutr Rev Date: 1998-01 Impact factor: 7.110

2. Oral administration of short-chain fatty acids reduces the intestinal mucositis caused by treatment with Ara-C in mice fed commercial or elemental diets.

Authors: M G Ramos; E A Bambirra; D C Cara; E C Vieira; J I Alvarez-Leite
Journal: Nutr Cancer Date: 1997 Impact factor: 2.900

3. Sodium butyrate inhibits carcinoma development in a 1,2-dimethylhydrazine-induced rat colon cancer.

Authors: V Medina; J J Afonso; H Alvarez-Arguelles; C Hernández; F González
Journal: JPEN J Parenter Enteral Nutr Date: 1998 Jan-Feb Impact factor: 4.016

4. Efficacy of different triglycerides in total parenteral nutrition for preventing atrophy of the gut in traumatized rats.

Authors: J Linseisen; G Wolfram
Journal: JPEN J Parenter Enteral Nutr Date: 1997 Jan-Feb Impact factor: 4.016

1 in total

Review 1. Recipe for IBD: can we use food to control inflammatory bowel disease?

Authors: Mario Witkowski; Marco Witkowski; Nicola Gagliani; Samuel Huber
Journal: Semin Immunopathol Date: 2017-11-09 Impact factor: 9.623

1 in total

Protection by short-chain fatty acids against 1-beta-D-arabinofuranosylcytosine-induced intestinal lesions in germfree mice.

Review 1. Short-chain fatty acids in ulcerative colitis.

2. Oral administration of short-chain fatty acids reduces the intestinal mucositis caused by treatment with Ara-C in mice fed commercial or elemental diets.

3. Sodium butyrate inhibits carcinoma development in a 1,2-dimethylhydrazine-induced rat colon cancer.

4. Efficacy of different triglycerides in total parenteral nutrition for preventing atrophy of the gut in traumatized rats.

5. Mediation of the trophic effects of short-chain fatty acids on the rat jejunum and colon.

6. Partition and absorption of valatile fatty acids in the alimentary canal of the rat.

7. Absorption of short-chain fatty acids from the human colon measured by the 14CO2 breath test.

8. Ketogenesis in the living rat followed by 13C NMR spectroscopy.

9. Effect of short-chain fatty acids on the secretory response of the ovine exocrine pancreas.

10. Effect of volatile fatty acids on blood flow and oxygen uptake by the dog colon.

Review 1. Recipe for IBD: can we use food to control inflammatory bowel disease?