| Literature DB >> 10099682 |
Abstract
Ion channels are the unitary elements that underlie electrical activity of gastrointestinal smooth muscle cells and of interstitial cells of Cajal. The result of ion channel activity in the gastrointestinal smooth muscle layers is a rhythmic change in membrane potential that in turn underlies events leading to organized motility patterns. Gastrointestinal smooth muscle cells and interstitial cells of Cajal express a wide variety of ion channels that are tightly regulated. This review summarizes 20 years of data obtained from patch-clamp studies on gastrointestinal smooth muscle cells and interstitial cells, with a focus on regulation.Mesh：
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Year: 1999 PMID： 10099682 DOI： 10.1146/annurev.physiol.61.1.45
Source DB: PubMed Journal: Annu Rev Physiol ISSN： 0066-4278 Impact factor: 19.318