Literature DB >> 10079974

Reoxygenation injury of human brain capillary endothelial cells.

T Nagashima1, S Wu, M Yamaguchi, N Tamaki.   

Abstract

1. Many studies have demonstrated that endothelial cells from several species can generate oxygen free radicals when subjected to anoxia and reoxygenation. However, due to the heterogeneity of the endothelium within different organs and species, the effects of superoxide dismutase (SOD), catalase, and allopurinol on reoxygenated cultured cells remain quite controversial. 2. This review outlines the possible sources of oxygen free radicals within brain endothelial cells. 3. We examine the aspects of the effects of SOD catalase and allopurinol on cultured human brain capillary endothelial cells upon reoxygenation. 4. Also, we introduce briefly a method of culturing human brain capillary endothelial cells and present our experimental results on the effects of SOD, catalase, and allopurinol in these cultured cells following anoxia and reoxygenation.

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Year:  1999        PMID: 10079974     DOI: 10.1023/a:1006980911551

Source DB:  PubMed          Journal:  Cell Mol Neurobiol        ISSN: 0272-4340            Impact factor:   5.046


  65 in total

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Journal:  Proc Natl Acad Sci U S A       Date:  1990-02       Impact factor: 11.205

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Journal:  Free Radic Biol Med       Date:  1990       Impact factor: 7.376

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Journal:  J Cell Physiol       Date:  1991-08       Impact factor: 6.384

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Journal:  Neurology       Date:  1984-03       Impact factor: 9.910

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Journal:  J Neurochem       Date:  1981-03       Impact factor: 5.372

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  1 in total

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Authors:  Yuqin Wu; Lin Fan; Yun Wang; Jing Ding; Rongfu Wang
Journal:  Inflammation       Date:  2021-05-17       Impact factor: 4.092

  1 in total

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