Literature DB >> 100785

Assignment of genes for immunoglobulin kappa and heavy chains to chromosomes 6 and 12 in mouse.

H Hengartner, T Meo, E Müller.   

Abstract

Using somatic cell hybrids from fusions of lymphocytes of two different mouse stocks with the myeloma cell line X63-Ag8, we have assigned genes for the immunoglobulin heavy and kappa-type light chains to chromosomes 12 and 6, respectively. The two mouse stocks exhibit karyotypes consisting of nine pairs of metacentric chromosomes as a result of centric fusions of acrocentric chromosomes in different combinations. In the hybrid cells these metacentric chromosomes can be distinguished from the acrocentric chromosomes of myeloma origin, permitting correlation of Ig chain expression with mitotic loss of individual metacentric chromosomes.

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Year:  1978        PMID： 100785      PMCID： PMC336142          DOI： 10.1073/pnas.75.9.4494

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  10 in total

1.  SELECTION OF HYBRIDS FROM MATINGS OF FIBROBLASTS IN VITRO AND THEIR PRESUMED RECOMBINANTS.

Authors:  J W LITTLEFIELD
Journal:  Science       Date:  1964-08-14       Impact factor: 47.728

2.  Robertsonian metacentrics in the mouse.

Authors:  E Capanna; A Gropp; H Winking; G Noack; M V Civitelli
Journal:  Chromosoma       Date:  1976-11-29       Impact factor: 4.316

3.  Intracellular immunoglobulin chain synthesis in non-secreting variants of a mouse myeloma: detection of inactive light-chain messenger RNA.

Authors:  N J Cowan; D S Secher; C Milstein
Journal:  J Mol Biol       Date:  1974-12-25       Impact factor: 5.469

4.  Cleavage of structural proteins during the assembly of the head of bacteriophage T4.

Authors:  U K Laemmli
Journal:  Nature       Date:  1970-08-15       Impact factor: 49.962

5.  Fusion between immunoglobulin-secreting and nonsecreting myeloma cell lines.

Authors:  G Köhler; S C Howe; C Milstein
Journal:  Eur J Immunol       Date:  1976-04       Impact factor: 5.532

6.  Genes for immunoglobulin heavy chain and serum prealbumin protein are linked in mouse.

Authors:  B A Taylor; D W Bailey; M Cherry; R Riblet; M Weigert
Journal:  Nature       Date:  1975-08-21       Impact factor: 49.962

7.  Dynamics of immunoglobulin genes.

Authors:  S Tonegawa; C Brack; N Hozumi; G Matthyssens; R Schuller
Journal:  Immunol Rev       Date:  1977       Impact factor: 12.988

8.  Surface markers and functional relationships of cells involved in murine B-lymphocyte differentiation.

Authors:  L A Herzenberg; L A Herzenberg; S J Black; M R Loken; K Okumura; W van der Loo; B A Osborne; D Hewgill; J W Goding; G Gutman; N L Warner
Journal:  Cold Spring Harb Symp Quant Biol       Date:  1977

9.  Derivation of specific antibody-producing tissue culture and tumor lines by cell fusion.

Authors:  G Köhler; C Milstein
Journal:  Eur J Immunol       Date:  1976-07       Impact factor: 5.532

10.  Characterization of the domestic horse (Equus caballus) karyotype using G- and C-banding techniques.

Authors:  R A Buckland; J M Fletcher; C Chandley
Journal:  Experientia       Date:  1976-09-15
  10 in total
  57 in total

Review 1.  Mouse chromosome 12.

Authors:  P D'Eustachio
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

Review 2.  Mouse chromosome 6.

Authors:  R W Elliott; K J Moore
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

3.  The mink gene for the lambda light immunoglobulin chain: characterization of cDNA and chromosomal localization.

Authors:  T M Khlebodarova; N M Matveeva; O L Serov; A M Najakshin; E S Belousov; S V Bogachev; O K Baranov
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

Review 4.  Mouse chromosome 12.

Authors:  P D'Eustachio
Journal:  Mamm Genome       Date:  1991       Impact factor: 2.957

Review 5.  Mouse map of paralogous genes.

Authors:  J H Nadeau; M Kosowsky
Journal:  Mamm Genome       Date:  1991       Impact factor: 2.957

Review 6.  T-cell clones and T-cell receptors.

Authors:  F W Fitch
Journal:  Microbiol Rev       Date:  1986-03

7.  Murine invariant chain gene: chromosomal assignment and segregation in recombinant inbred strains.

Authors:  J E Richards; D D Pravtcheva; C Day; F H Ruddle; P P Jones
Journal:  Immunogenetics       Date:  1985       Impact factor: 2.846

8.  Gene localization on sorted chromosomes: definitive evidence on the relative positioning of genes participating in the mouse plasmacytoma-associated typical translocation.

Authors:  Z Wirschubsky; S Ingvarsson; A Carstenssen; F Wiener; G Klein; J Sümegi
Journal:  Proc Natl Acad Sci U S A       Date:  1985-10       Impact factor: 11.205

Review 9.  Somatic cell fusion as a source of genetic rearrangement leading to metastatic variants.

Authors:  L Larizza; V Schirrmacher
Journal:  Cancer Metastasis Rev       Date:  1984       Impact factor: 9.264

10.  Conserved regions of homologous G-banded chromosomes between orders in mammalian evolution: carnivores and primates.

Authors:  W G Nash; S J O'Brien
Journal:  Proc Natl Acad Sci U S A       Date:  1982-11       Impact factor: 11.205
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