Literature DB >> 10075773

Norpregnane glycosides from a Thai soft coral, Scleronephthya pallida.

P Kittakoop1, R Suttisri, C Chaichantipyuth, S Vethchagarun, K Suwanborirux.   

Abstract

Two new norpregnane glycosides, 19-norpregna-1,3,5(10), 20-tetraen-3-O-alpha-fucopyranoside (3) and 19-norpregna-1,3,5(10), 20-tetraen-3-O-beta-arabinopyranoside (4), were isolated from the soft coral Scleronephthya pallida, along with two known steroids, pregna-1,20-dien-3-one (1) and 19-norpregna-1,3,5(10), 20-tetraen-3-ol (2). 19-Norpregna-1,3,5(10), 20-tetraen-3-O-alpha-fucopyranoside (3) exhibits moderate antimalarial and cytotoxic activities. The chemical structures of 1-4 were elucidated from spectroscopic data.

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Year:  1999        PMID: 10075773     DOI: 10.1021/np980273w

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  5 in total

1.  Myrmenaphthol A, Isolated from a Hawaiian Sponge of the Genus Myrmekioderma.

Authors:  Stephen M Parrish; Ram P Neupane; Mary Kay Harper; John Head; Philip G Williams
Journal:  J Nat Prod       Date:  2019-08-28       Impact factor: 4.050

2.  5α-Pregna-1,20-dien-3-one.

Authors:  Guang-Ying Chen; Mei-Yan Wei; Ni Tan; Zhen Liu; Rui-Yun Yang
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2010-01-13

3.  Cytotoxic and anti-inflammatory metabolites from the soft coral Scleronephthya gracillimum.

Authors:  Hui-Yu Fang; Chi-Hsin Hsu; Chih-Hua Chao; Zhi-Hong Wen; Yang-Chang Wu; Chang-Feng Dai; Jyh-Horng Sheu
Journal:  Mar Drugs       Date:  2013-05-29       Impact factor: 5.118

Review 4.  Cytotoxic and cytolytic cnidarian venoms. A review on health implications and possible therapeutic applications.

Authors:  Gian Luigi Mariottini; Luigi Pane
Journal:  Toxins (Basel)       Date:  2013-12-27       Impact factor: 4.546

5.  Pregnane-type steroids from the Formosan soft coral Scleronephthya flexilis.

Authors:  Chao-Ying Kuo; Yung-Shun Juan; Mei-Chin Lu; Michael Yen-Nan Chiang; Chang-Feng Dai; Yang-Chang Wu; Ping-Jyun Sung
Journal:  Int J Mol Sci       Date:  2014-06-06       Impact factor: 5.923

  5 in total

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