Literature DB >> 10067273

The synthesis and antiviral activity of 4-fluoro-1-beta-D-ribofuranosyl-1H-pyrazole-3-carboxamide.

R Storer1, C J Ashton, A D Baxter, M M Hann, C L Marr, A M Mason, C L Mo, P L Myers, S A Noble, C R Penn, N G Weir, J M Woods, P L Coe.   

Abstract

A novel fluoropyrazole ribonucleoside has been shown to have significant anti-influenza activity in vitro. The compound is compared and contrasted with the structurally-related compound ribavirin in attempts to identify factors having significant bearing on the mode of action of both compounds.

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Year:  1999        PMID: 10067273     DOI: 10.1080/15257779908043068

Source DB:  PubMed          Journal:  Nucleosides Nucleotides        ISSN: 0732-8311


  3 in total

Review 1.  Synthesis and Pharmacological Activities of Pyrazole Derivatives: A Review.

Authors:  Khalid Karrouchi; Smaail Radi; Youssef Ramli; Jamal Taoufik; Yahia N Mabkhot; Faiz A Al-Aizari; M'hammed Ansar
Journal:  Molecules       Date:  2018-01-12       Impact factor: 4.411

2.  Synthesis, anti-inflammatory, analgesic, COX1/2-inhibitory activity, and molecular docking studies of hybrid pyrazole analogues.

Authors:  Md Jahangir Alam; Ozair Alam; Suroor Ahmad Khan; Mohd Javed Naim; Mohammad Islamuddin; Girdhar Singh Deora
Journal:  Drug Des Devel Ther       Date:  2016-10-31       Impact factor: 4.162

3.  Synthetic, Structural, and Anticancer Activity Evaluation Studies on Novel Pyrazolylnucleosides.

Authors:  Yogesh Yadav; Deepti Sharma; Kumar Kaushik; Vineet Kumar; Amitabh Jha; Ashok K Prasad; Christophe Len; Sanjay V Malhotra; Jesper Wengel; Virinder S Parmar
Journal:  Molecules       Date:  2019-10-30       Impact factor: 4.411

  3 in total

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