Literature DB >> 10052960

Major groove binding and 'DNA-induced' fit in the intercalation of a derivative of the mixed topoisomerase I/II poison N-(2-(dimethylamino)ethyl)acridine-4-carboxamide (DACA) into DNA: X-ray structure complexed to d(CG(5-BrU)ACG)2 at 1.3-A resolution.

A K Todd1, A Adams, J H Thorpe, W A Denny, L P Wakelin, C J Cardin.   

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Year:  1999        PMID: 10052960     DOI: 10.1021/jm980479u

Source DB:  PubMed          Journal:  J Med Chem        ISSN: 0022-2623            Impact factor:   7.446


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  18 in total

1.  Bioactive principles in the bark of Pilidiostigma tropicum.

Authors:  William N Setzer; Glenn F Rozmus; Mary C Setzer; Jennifer M Schmidt; Bernhard Vogler; Sabine Reeb; Betsy R Jackes; Anthony K Irvine
Journal:  J Mol Model       Date:  2006-04-07       Impact factor: 1.810

2.  Crystal structure of 9-amino-N-[2-(4-morpholinyl)ethyl]-4-acridinecarboxamide bound to d(CGTACG)2: implications for structure-activity relationships of acridinecarboxamide topoisomerase poisons.

Authors:  Adrienne Adams; J Mitchell Guss; William A Denny; Laurence P G Wakelin
Journal:  Nucleic Acids Res       Date:  2002-02-01       Impact factor: 16.971

3.  Acridine-N peptide conjugates display enhanced affinity and specificity for boxB RNA targets.

Authors:  Xin Qi; Tianbing Xia; Richard W Roberts
Journal:  Biochemistry       Date:  2010-07-13       Impact factor: 3.162

4.  Sequence specificity in DNA-drug intercalation: MD simulation and density functional theory approaches.

Authors:  Lakshmi Maganti; Dhananjay Bhattacharyya
Journal:  J Comput Aided Mol Des       Date:  2019-12-09       Impact factor: 3.686

5.  Variable role of ions in two drug intercalation complexes of DNA.

Authors:  Núria Valls; Roberto A Steiner; Glenford Wright; Garib N Murshudov; Juan A Subirana
Journal:  J Biol Inorg Chem       Date:  2005-09-23       Impact factor: 3.358

6.  Crystal structures of Λ-[Ru(phen)₂dppz]²⁺ with oligonucleotides containing TA/TA and AT/AT steps show two intercalation modes.

Authors:  Hakan Niyazi; James P Hall; Kyra O'Sullivan; Graeme Winter; Thomas Sorensen; John M Kelly; Christine J Cardin
Journal:  Nat Chem       Date:  2012-06-24       Impact factor: 24.427

7.  A novel form of intercalation involving four DNA duplexes in an acridine-4-carboxamide complex of d(CGTACG)(2).

Authors:  A Adams; J M Guss; C A Collyer; W A Denny; L P Wakelin
Journal:  Nucleic Acids Res       Date:  2000-11-01       Impact factor: 16.971

Review 8.  DNA Recognition by a Novel Bis-Intercalator, Potent Anticancer Drug XR5944.

Authors:  Clement Lin; Danzhou Yang
Journal:  Curr Top Med Chem       Date:  2015       Impact factor: 3.295

Review 9.  Recent Advances in Copper Intercalators as Anticancer Agents.

Authors:  C Shobha Devi; B Thulasiram; Rajeshwar Rao Aerva; Penumaka Nagababu
Journal:  J Fluoresc       Date:  2018-08-31       Impact factor: 2.217

Review 10.  Interfacial inhibitors.

Authors:  Yves Pommier; Evgeny Kiselev; Christophe Marchand
Journal:  Bioorg Med Chem Lett       Date:  2015-07-18       Impact factor: 2.823

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