| Literature DB >> 10049293 |
T Matsumoto1, K Tateda, S Miyazaki, N Furuya, A Ohno, Y Ishii, Y Hirakata, K Yamaguchi.
Abstract
To determine the mechanisms of immunomodulating action of fosfomycin (FOF), we examined its effect on the production of inflammatory cytokines in mice injected with lipopolysaccharide (LPS). Treatment with FOF significantly lowered the peak serum levels of tumor necrosis factor alpha and interleukin-1 beta, indicating that FOF alters inflammatory cytokine production after LPS stimulation.Entities:
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Year: 1999 PMID: 10049293 PMCID: PMC89186
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191