Literature DB >> 10047588

The fundamentals of protein folding: bringing together theory and experiment.

C M Dobson1, M Karplus.   

Abstract

Experimental and theoretical studies together are providing insights into the mechanism by which proteins fold. Our present knowledge of the essential aspects of the folding reaction is outlined and some approaches, both theoretical and experimental, that are being developed to obtain a more detailed understanding of this complex process are described.

Mesh:

Year:  1999        PMID: 10047588     DOI: 10.1016/s0959-440x(99)80012-8

Source DB:  PubMed          Journal:  Curr Opin Struct Biol        ISSN: 0959-440X            Impact factor:   6.809


  85 in total

1.  An amino acid code for protein folding.

Authors:  J Rumbley; L Hoang; L Mayne; S W Englander
Journal:  Proc Natl Acad Sci U S A       Date:  2001-01-02       Impact factor: 11.205

2.  A theoretical search for folding/unfolding nuclei in three-dimensional protein structures.

Authors:  O V Galzitskaya; A V Finkelstein
Journal:  Proc Natl Acad Sci U S A       Date:  1999-09-28       Impact factor: 11.205

3.  Dependence and independence of [PSI(+)] and [PIN(+)]: a two-prion system in yeast?

Authors:  I L Derkatch; M E Bradley; S V Masse; S P Zadorsky; G V Polozkov; S G Inge-Vechtomov; S W Liebman
Journal:  EMBO J       Date:  2000-05-02       Impact factor: 11.598

4.  Change in backbone torsion angle distribution on protein folding.

Authors:  A J Petrescu; P Calmettes; D Durand; V Receveur; J C Smith
Journal:  Protein Sci       Date:  2000-06       Impact factor: 6.725

5.  Macromolecular crowding perturbs protein refolding kinetics: implications for folding inside the cell.

Authors:  B van den Berg; R Wain; C M Dobson; R J Ellis
Journal:  EMBO J       Date:  2000-08-01       Impact factor: 11.598

6.  Multistep nucleus formation and a separate subunit contribution of the amyloidgenesis of heat-denatured monellin.

Authors:  T Konno
Journal:  Protein Sci       Date:  2001-10       Impact factor: 6.725

7.  Folding simulations of a three-stranded antiparallel beta -sheet peptide.

Authors:  P Ferrara; A Caflisch
Journal:  Proc Natl Acad Sci U S A       Date:  2000-09-26       Impact factor: 11.205

8.  Role of hydrophobic clusters and long-range contact networks in the folding of (alpha/beta)8 barrel proteins.

Authors:  S Selvaraj; M Michael Gromiha
Journal:  Biophys J       Date:  2003-03       Impact factor: 4.033

9.  Refolding of a high molecular weight protein: salt effect on collapse.

Authors:  D Lairez; E Pauthe; J Pelta
Journal:  Biophys J       Date:  2003-06       Impact factor: 4.033

10.  The origins of asymmetry in the folding transition states of protein L and protein G.

Authors:  John Karanicolas; Charles L Brooks
Journal:  Protein Sci       Date:  2002-10       Impact factor: 6.725

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