Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 T cell mediated immunity to Mycobacterium tuberculosis.

Literature DB >> 10047556

T cell mediated immunity to Mycobacterium tuberculosis.

Abstract

Recent advances in the characterization of the protective immune response to mycobacteria have highlighted the central role of phenotypically and functionally distinct subsets of T cells. These T cell subsets not only contribute to host defense by the secretion of macrophage-activating cytokines, but also by lysing the host cell. Besides releasing intracellular pathogens, which can then be taken up and killed by newly recruited macrophages, it has now been demonstrated that lysis of infected targets by one subset of cytolytic T cells can directly kill Mycobacterium tuberculosis.

Entities: Species

Mesh：

Substances：

Year: 1999 PMID： 10047556 DOI： 10.1016/s1369-5274(99)80015-0

Source DB: PubMed Journal: Curr Opin Microbiol ISSN： 1369-5274 Impact factor: 7.934

Keyword Cloud
Cited

36 in total

1. Protective immunity against Mycobacterium tuberculosis induced by dendritic cells pulsed with both CD8(+)- and CD4(+)-T-cell epitopes from antigen 85A.

Authors: Helen McShane; Shahriar Behboudi; Nilu Goonetilleke; Roger Brookes; Adrian V S Hill
Journal: Infect Immun Date: 2002-03 Impact factor: 3.441

Review 2. Role of cytokines in the innate immune response to intracellular pathogens.

Authors: S Stenger; M Röllinghoff
Journal: Ann Rheum Dis Date: 2001-11 Impact factor: 19.103

3. Antibacterial effect of human V gamma 2V delta 2 T cells in vivo.

Authors: L Wang; A Kamath; H Das; L Li; J F Bukowski
Journal: J Clin Invest Date: 2001-11 Impact factor: 14.808

4. Evaluation of the safety and immunogenicity of two antigen concentrations of the Mtb72F/AS02(A) candidate tuberculosis vaccine in purified protein derivative-negative adults.

Authors: Isabel Leroux-Roels; Geert Leroux-Roels; Opokua Ofori-Anyinam; Philippe Moris; Els De Kock; Frédéric Clement; Marie-Claude Dubois; Marguerite Koutsoukos; Marie-Ange Demoitié; Joe Cohen; W Ripley Ballou
Journal: Clin Vaccine Immunol Date: 2010-09-22

5. Low dose chronic Schistosoma mansoni infection increases susceptibility to Mycobacterium bovis BCG infection in mice.

Authors: D Elias; H Akuffo; C Thors; A Pawlowski; S Britton
Journal: Clin Exp Immunol Date: 2005-03 Impact factor: 4.330

Review 6. Association of polymorphism +874 A/T of interferon-γ and susceptibility to the development of tuberculosis: meta-analysis.

Authors: A C de Albuquerque; L Q Rocha; A H de Morais Batista; A B Teixeira; D B Dos Santos; N A P Nogueira
Journal: Eur J Clin Microbiol Infect Dis Date: 2012-06-09 Impact factor: 3.267

T cell mediated immunity to Mycobacterium tuberculosis.

1. Protective immunity against Mycobacterium tuberculosis induced by dendritic cells pulsed with both CD8(+)- and CD4(+)-T-cell epitopes from antigen 85A.

Review 2. Role of cytokines in the innate immune response to intracellular pathogens.

3. Antibacterial effect of human V gamma 2V delta 2 T cells in vivo.

4. Evaluation of the safety and immunogenicity of two antigen concentrations of the Mtb72F/AS02(A) candidate tuberculosis vaccine in purified protein derivative-negative adults.

5. Low dose chronic Schistosoma mansoni infection increases susceptibility to Mycobacterium bovis BCG infection in mice.

Review 6. Association of polymorphism +874 A/T of interferon-γ and susceptibility to the development of tuberculosis: meta-analysis.

7. Metastatic melanoma secreted IL-10 down-regulates CD1 molecules on dendritic cells in metastatic tumor lesions.

Review 8. Infections in patients with inherited defects in phagocytic function.

9. Selected pool of peptides from ESAT-6 and CFP-10 proteins for detection of Mycobacterium tuberculosis infection.

10. Immune cellular parameters of leprosy and human immunodeficiency virus-1 co-infected subjects.