Literature DB >> 10047549

Molecular and cellular biology of pneumococcal infection.

E Tuomanen1.   

Abstract

The complete pneumococcal genome sequence was released in November, 1997. This advance has been combined with new understanding of physiology and pathogenesis including characterization of a family of surface proteins adducted to choline, regulation of virulence, and the regulon for natural DNA transformation. These developments in our understanding of molecular and cellular biology of pneumococcal infection will allow the development of new vaccines and antibiotics against this community acquired pathogen.

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Year:  1999        PMID： 10047549     DOI： 10.1016/s1369-5274(99)80006-x

Source DB:  PubMed          Journal:  Curr Opin Microbiol        ISSN： 1369-5274            Impact factor:   7.934


  24 in total

1.  The autolytic enzyme LytA of Streptococcus pneumoniae is not responsible for releasing pneumolysin.

Authors:  P Balachandran; S K Hollingshead; J C Paton; D E Briles
Journal:  J Bacteriol       Date:  2001-05       Impact factor: 3.490

Review 2.  Clinical implications of the specialised B cell response to polysaccharide encapsulated pathogens.

Authors:  C G Vinuesa; C de Lucas; M C Cook
Journal:  Postgrad Med J       Date:  2001-09       Impact factor: 2.401

3.  A major locus conferring susceptibility to infection by Streptococcus pneumoniae in mice.

Authors:  Paul Denny; Elaine Hopes; Neill Gingles; Karl W Broman; William McPheat; John Morten; Janet Alexander; Peter W Andrew; Steve D M Brown
Journal:  Mamm Genome       Date:  2003-07       Impact factor: 2.957

4.  Sialidase-based anti-influenza virus therapy protects against secondary pneumococcal infection.

Authors:  Maria Hedlund; Laura M Aschenbrenner; Kellie Jensen; Jeffrey L Larson; Fang Fang
Journal:  J Infect Dis       Date:  2010-04-01       Impact factor: 5.226

5.  Expression of phosphorylcholine by Histophilus somni induces bovine platelet aggregation.

Authors:  Christopher J Kuckleburg; Shaadi F Elswaifi; Thomas J Inzana; Charles J Czuprynski
Journal:  Infect Immun       Date:  2006-11-21       Impact factor: 3.441

6.  Catabolite control protein A (CcpA) contributes to virulence and regulation of sugar metabolism in Streptococcus pneumoniae.

Authors:  Ramkumar Iyer; Nitin S Baliga; Andrew Camilli
Journal:  J Bacteriol       Date:  2005-12       Impact factor: 3.490

7.  Differential activation of the immune system by virulent Streptococcus pneumoniae strains determines recovery or death of the host.

Authors:  Y Mizrachi-Nebenzahl; S Lifshitz; R Teitelbaum; S Novick; A Levi; D Benharroch; E Ling; R Dagan
Journal:  Clin Exp Immunol       Date:  2003-10       Impact factor: 4.330

8.  Accumulation of partly folded states in the equilibrium unfolding of the pneumococcal choline-binding module C-LytA.

Authors:  Beatriz Maestro; Jesús M Sanz
Journal:  Biochem J       Date:  2005-04-15       Impact factor: 3.857

9.  The ClpP protease of Streptococcus pneumoniae modulates virulence gene expression and protects against fatal pneumococcal challenge.

Authors:  Hyog-Young Kwon; A David Ogunniyi; Moo-Hyun Choi; Suhk-Neung Pyo; Dong-Kwon Rhee; James C Paton
Journal:  Infect Immun       Date:  2004-10       Impact factor: 3.441

10.  A pneumococcal pilus influences virulence and host inflammatory responses.

Authors:  M A Barocchi; J Ries; X Zogaj; C Hemsley; B Albiger; A Kanth; S Dahlberg; J Fernebro; M Moschioni; V Masignani; K Hultenby; A R Taddei; K Beiter; F Wartha; A von Euler; A Covacci; D W Holden; S Normark; R Rappuoli; B Henriques-Normark
Journal:  Proc Natl Acad Sci U S A       Date:  2006-02-15       Impact factor: 11.205
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