Literature DB >> 10029928

Women's interest in vaginal microbicides.

J E Darroch1, J J Frost.   

Abstract

CONTEXT: Each year, an estimated 15 million new cases of sexually transmitted diseases (STDs), including HIV, occur in the United States. Women are not only at a disadvantage because of their biological and social susceptibility, but also because of the methods that are available for prevention.
METHODS: A nationally representative sample of 1,000 women aged 18-44 in the continental United States who had had sex with a man in the last 12 months were interviewed by telephone. Analyses identified levels and predictors of women's worry about STDs and interest in vaginal microbicides, as well as their preferences regarding method characteristics. Numbers of potential U.S. microbicide users were estimated.
RESULTS: An estimated 21.3 million U.S. women have some potential current interest in using a microbicidal product. Depending upon product specifications and cost, as many as 6.0 million women who are worried about getting an STD would be very interested in current use of a microbicide. These women are most likely to be unmarried and not cohabiting, of low income and less education, and black or Hispanic. They also are more likely to have visited a doctor for STD symptoms or to have reduced their sexual activity because of STDs, to have a partner who had had other partners in the past year, to have no steady partner or to have ever used condoms for STD prevention.
CONCLUSIONS: A significant minority of women in the United States are worried about STDs and think they would use vaginal microbicides. The development, testing and marketing of such products should be expedited.

Entities:  

Keywords:  Americas; Contraception; Contraceptive Methods; Contraceptive Usage; Developed Countries; Diseases; Economic Factors; Family Planning; Hiv Infections--prevention and control; Infections; Method Acceptability--women; North America; Northern America; Reproductive Tract Infections; Research And Development; Research Methodology; Research Report; Sampling Studies; Sexually Transmitted Diseases--prevention and control; Sexually Transmitted Diseases--women; Studies; Surveys; Technology; United States; Vaginal Spermicides; Viral Diseases; Women

Mesh:

Substances:

Year:  1999        PMID: 10029928

Source DB:  PubMed          Journal:  Fam Plann Perspect        ISSN: 0014-7354


  32 in total

1.  An Update on Vaginal Microbicides.

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Journal:  Curr Infect Dis Rep       Date:  2001-12       Impact factor: 3.725

2.  Development of a liposome microbicide formulation for vaginal delivery of octylglycerol for HIV prevention.

Authors:  Lin Wang; Alexandra Beumer Sassi; Dorothy Patton; Charles Isaacs; B J Moncla; Phalguni Gupta; Lisa Cencia Rohan
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3.  Retrocyclin RC-101 blocks HIV-1 transmission across cervical mucosa in an organ culture.

Authors:  Phalguni Gupta; Deena Ratner; Ming Ding; Bruce Patterson; Lisa C Rohan; Todd A Reinhart; Velpandi Ayyavoo; Xioli Huang; Dorothy L Patton; Bharat Ramratnam; Alexander M Cole
Journal:  J Acquir Immune Defic Syndr       Date:  2012-08-15       Impact factor: 3.731

4.  Willingness to use microbicides is affected by the importance of product characteristics, use parameters, and protective properties.

Authors:  Kathleen M Morrow; Joseph L Fava; Rochelle K Rosen; Sara Vargas; Candelaria Barroso; Anna L Christensen; Cynthia Woodsong; Lawrence Severy
Journal:  J Acquir Immune Defic Syndr       Date:  2007-05-01       Impact factor: 3.731

5.  The vaginal microbiome in health and disease.

Authors:  Bryan A White; Douglas J Creedon; Karen E Nelson; Brenda A Wilson
Journal:  Trends Endocrinol Metab       Date:  2011-07-13       Impact factor: 12.015

6.  Contraceptive efficacy, acceptability, and safety of C31G and nonoxynol-9 spermicidal gels: a randomized controlled trial.

Authors:  Anne E Burke; Kurt Barnhart; Jeffrey T Jensen; Mitchell D Creinin; Terri L Walsh; Livia S Wan; Carolyn Westhoff; Michael Thomas; David Archer; Hongsheng Wu; James Liu; William Schlaff; Bruce R Carr; Diana Blithe
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7.  Acceptability of hypothetical microbicides among women in sex establishments in rural areas in Southern China.

Authors:  Yu Wang; Su-Su Liao; Margaret R Weeks; Jing-Mei Jiang; Maryann Abbott; Yue-Jiao Zhou; Bin He; Wei Liu; Katie E Mosack
Journal:  Sex Transm Dis       Date:  2008-01       Impact factor: 2.830

Review 8.  Vaginal drug delivery systems for HIV prevention.

Authors:  Lisa Cencia Rohan; Alexandra B Sassi
Journal:  AAPS J       Date:  2009-02-05       Impact factor: 4.009

9.  Microbicide acceptability among female sex workers in Beijing, China: results from a pilot study.

Authors:  Lin Han; Fan Lv; Peng Xu; Guolei Zhang; Naomi S Juniper; Zhenglai Wu
Journal:  J Womens Health (Larchmt)       Date:  2009-09       Impact factor: 2.681

10.  Young women's contraceptive microbicide preferences: associations with contraceptive behavior and sexual relationship characteristics.

Authors:  Candace Best; Amanda E Tanner; Devon J Hensel; J Dennis Fortenberry; Gregory D Zimet
Journal:  Perspect Sex Reprod Health       Date:  2013-12-10
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