Literature DB >> 10029393

Shrinking of polypropylene mesh in vivo: an experimental study in dogs.

U Klinge1, B Klosterhalfen, M Müller, A P Ottinger, V Schumpelick.   

Abstract

OBJECTIVE: To assess the extent of shrinkage of meshes used for hernia repair.
DESIGN: Experimental study in dogs.
SETTING: University hospital, Germany and University Research Centre, Moscow. ANIMALS: 10 dogs had monofilament polypropylene meshes that weighed 95 g/m2 (Marlex) or multifilament reduced polypropylene meshes combined with polyglactin 910 that weighed 55 g/m2 (Soft Hernia Mesh) implanted for either 3 or 6 months. MAIN OUTCOME MEASURES: Histological appearance and radiological assessment of the position and area of the mesh.
RESULTS: After 4 weeks the area of mesh in the monofilament group was reduced from to 139 (11) to 75 (8) cm2 (54%) and that of the multifilament from 116 (18) to 77 (20) cm2 (66%). The multifilament mesh with the reduced amount of polypropylene showed less inflammatory response and less shrinkage. The mesh did not seem to have moved.
CONCLUSION: Meshes that contain a lot of polypropylene shrink to about 30%-50% of their original size after 4 weeks, requiring an overlap of at least 3 cm if implanted subfascially. Reduction in the polypropylene content decreases both the inflammatory response and the shrinkage. Meshes with big pores are less likely to fold and improve compatibility.

Entities:  

Mesh:

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Year:  1998        PMID: 10029393     DOI: 10.1080/110241598750005156

Source DB:  PubMed          Journal:  Eur J Surg        ISSN: 1102-4151


  77 in total

1.  Does every hernia demand a mesh repair? A critical review.

Authors:  V Schumpelick
Journal:  Hernia       Date:  2001-03       Impact factor: 4.739

2.  Histologic and biomechanical evaluation of a novel macroporous polytetrafluoroethylene knit mesh compared to lightweight and heavyweight polypropylene mesh in a porcine model of ventral incisional hernia repair.

Authors:  L Melman; E D Jenkins; N A Hamilton; L C Bender; M D Brodt; C R Deeken; S C Greco; M M Frisella; B D Matthews
Journal:  Hernia       Date:  2011-01-30       Impact factor: 4.739

3.  Lichtenstein tension-free hernioplasty: its inception, evolution, and principles.

Authors:  Parviz K Amid
Journal:  Hernia       Date:  2003-09-20       Impact factor: 4.739

Review 4.  Inguinal hernia repair: current surgical techniques.

Authors:  R Bittner; J Schwarz
Journal:  Langenbecks Arch Surg       Date:  2011-11-25       Impact factor: 3.445

5.  Shrinkage of intraperitoneal onlay mesh in sheep: coated polyester mesh versus covered polypropylene mesh.

Authors:  N B Zinther; P Wara; H Friis-Andersen
Journal:  Hernia       Date:  2010-06-02       Impact factor: 4.739

6.  Polypropylene, polyester or polytetrafluoroethylene-is there an ideal material for mesh augmentation at the esophageal hiatus? Results from an experimental study in a porcine model.

Authors:  B P Müller-Stich; J D Senft; F Lasitschka; M Shevchenko; A T Billeter; T Bruckner; H G Kenngott; L Fischer; T Gehrig
Journal:  Hernia       Date:  2014-08-27       Impact factor: 4.739

7.  Comparative investigation of alloplastic materials for hernia repair with improved methodology.

Authors:  M Kapischke; K Prinz; J Tepel; J Tensfeldt; T Schulz
Journal:  Surg Endosc       Date:  2005-07-14       Impact factor: 4.584

8.  Relationship between tissue ingrowth and mesh contraction.

Authors:  Rodrigo Gonzalez; Kim Fugate; David McClusky; E Matt Ritter; Andrew Lederman; Dirk Dillehay; C Daniel Smith; Bruce J Ramshaw
Journal:  World J Surg       Date:  2005-08       Impact factor: 3.352

9.  Fibrin sealing versus stapling of hernia meshes in an onlay model in the rat.

Authors:  Alexander H Petter-Puchner; R Fortelny; R Mittermayr; W Ohlinger; H Redl
Journal:  Hernia       Date:  2005-08-02       Impact factor: 4.739

10.  Is a circular polypropylene mesh appropriate for application at the esophageal hiatus? Results from an experimental study in a porcine model.

Authors:  Beat P Müller-Stich; Arianeb Mehrabi; Hannes G Kenngott; Hamidreza Fonouni; Michael A Reiter; Gani Kuttymoratov; Felix Nickel; Georg R Linke; Ivo Wolf; Jörg Köninger; Carsten N Gutt
Journal:  Surg Endosc       Date:  2008-10-15       Impact factor: 4.584

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