Literature DB >> 10021921

A synthetic glycopeptide of human myelin oligodendrocyte glycoprotein to detect antibody responses in multiple sclerosis and other neurological diseases.

S Mazzucco1, S Matà, M Vergelli, R Fioresi, E Nardi, B Mazzanti, M Chelli, F Lolli, M Ginanneschi, F Pinto, L Massacesi, A M Papini.   

Abstract

Glycopeptides of hMOG(30-50) containing a glucosyl moiety on the side-chains of Asn, Ser or Hyp at position 31 were synthesised. Antibody titres to hMOG(30-50) and to its glucoderivatives were measured by ELISA in sera of patients affected by different neurological diseases. Anti-hMOG(30-50) antibodies were detected only using the glycopeptide [Asn31(N-Glc)]hMOG(30-50).

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Year:  1999        PMID： 10021921     DOI： 10.1016/s0960-894x(98)00698-2

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  9 in total

1.  An N-glucosylated peptide detecting disease-specific autoantibodies, biomarkers of multiple sclerosis.

Authors:  Francesco Lolli; Barbara Mulinacci; Alfonso Carotenuto; Bruno Bonetti; Giuseppina Sabatino; Benedetta Mazzanti; Anna Maria D'Ursi; Ettore Novellino; Marta Pazzagli; Laura Lovato; Maria C Alcaro; Elisa Peroni; Maria C Pozo-Carrero; Francesca Nuti; Luca Battistini; Giovanna Borsellino; Mario Chelli; Paolo Rovero; Anna Maria Papini
Journal:  Proc Natl Acad Sci U S A       Date:  2005-07-12       Impact factor: 11.205

2.  Elevated intrathecal myelin oligodendrocyte glycoprotein antibodies in multiple sclerosis.

Authors:  Eric C Klawiter; Laura Piccio; Jeri-Anne Lyons; Robert Mikesell; Kevin C O'Connor; Anne H Cross
Journal:  Arch Neurol       Date:  2010-09

3.  Autoantibodies against central nervous system antigens in a subset of B cell-dominant multiple sclerosis patients.

Authors:  Stefanie Kuerten; Tobias V Lanz; Nithya Lingampalli; Lauren J Lahey; Christoph Kleinschnitz; Mathias Mäurer; Michael Schroeter; Stefan Braune; Tjalf Ziemssen; Peggy P Ho; William H Robinson; Lawrence Steinman
Journal:  Proc Natl Acad Sci U S A       Date:  2020-08-18       Impact factor: 11.205

4.  Environmental pathways to autoimmune diseases: the cases of primary biliary cirrhosis and multiple sclerosis.

Authors:  Carlo Selmi; Anna Maria Papini; Piera Pugliese; Maria Claudia Alcaro; M Eric Gershwin
Journal:  Arch Med Sci       Date:  2011-07-11       Impact factor: 3.318

5.  Glycopeptide-based antibody detection in multiple sclerosis by surface plasmon resonance.

Authors:  Feliciana Real-Fernández; Irene Passalacqua; Elisa Peroni; Mario Chelli; Francesco Lolli; Anna Maria Papini; Paolo Rovero
Journal:  Sensors (Basel)       Date:  2012-05-02       Impact factor: 3.576

6.  The glycan role in the glycopeptide immunogenicity revealed by atomistic simulations and spectroscopic experiments on the multiple sclerosis biomarker CSF114(Glc).

Authors:  Agostino Bruno; Mario Scrima; Ettore Novellino; Gerardino D'Errico; Anna Maria D'Ursi; Vittorio Limongelli
Journal:  Sci Rep       Date:  2015-03-17       Impact factor: 4.379

7.  Interaction Study of Phospholipid Membranes with an N-Glucosylated β-Turn Peptide Structure Detecting Autoantibodies Biomarkers of Multiple Sclerosis.

Authors:  Lucia Becucci; Stefano Benci; Francesca Nuti; Feliciana Real-Fernandez; Zahra Vaezi; Lorenzo Stella; Mariano Venanzi; Paolo Rovero; Anna Maria Papini
Journal:  Membranes (Basel)       Date:  2015-09-30

8.  Antibodies from multiple sclerosis patients preferentially recognize hyperglucosylated adhesin of non-typeable Haemophilus influenzae.

Authors:  Marthe T C Walvoort; Chiara Testa; Raya Eilam; Rina Aharoni; Francesca Nuti; Giada Rossi; Feliciana Real-Fernandez; Roberta Lanzillo; Vincenzo Brescia Morra; Francesco Lolli; Paolo Rovero; Barbara Imperiali; Anna Maria Papini
Journal:  Sci Rep       Date:  2016-12-23       Impact factor: 4.379

9.  Amyloid-like Behavior of Site-Specifically Citrullinated Myelin Oligodendrocyte Protein (MOG) Peptide Fragments inside EBV-Infected B-Cells Influences Their Cytotoxicity and Autoimmunogenicity.

Authors:  Can Araman; Miriam E van Gent; Nico J Meeuwenoord; Nicole Heijmans; Mikkel H S Marqvorsen; Ward Doelman; Bart W Faber; Bert A 't Hart; Sander I Van Kasteren
Journal:  Biochemistry       Date:  2019-01-14       Impact factor: 3.162
  9 in total

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