Literature DB >> 1000131

Inhibition by amiloride of sodium-dependent fluid reabsorption in the rat isolated caudal epididymis.

P Y Wong, C H Yeung.   

Abstract

The rate of fluid reabsorption was studied in the rat isolated caudal epididymal sac in vitro. 2 Part of the fluid reabsorption was found to be dependent on intraluminal Na+. Amiloride (0.1 mM) completely inhibited this component of fluid reabsorption. 3 The log dose-inhibition curve to amiloride was sigmoid and the IC50 value was found to be 1.6 muM.

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Year:  1976        PMID： 1000131      PMCID： PMC1667476          DOI： 10.1111/j.1476-5381.1976.tb08620.x

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN： 0007-1188            Impact factor:   8.739


  3 in total

1.  Effects of triamterene and amiloride on urinary acidification and potassium excretion in the rat.

Authors:  J P Guignard; G Peters
Journal:  Eur J Pharmacol       Date:  1970-05       Impact factor: 4.432

2.  Amiloride inhibition of ion transport in perfused excretory duct of rat submaxillary gland.

Authors:  L H Schneyer
Journal:  Am J Physiol       Date:  1970-10

3.  Micropuncture studies of the electrochemical aspects of fluid and electrolyte transport in individual seminiferous tubules, the epididymis and the vas deferens in rats.

Authors:  N Levine; D J Marsh
Journal:  J Physiol       Date:  1971-03       Impact factor: 5.182
  3 in total
  6 in total

Review 1.  Organic and inorganic transporters of the testis: A review.

Authors:  David M Klein; Nathan J Cherrington
Journal:  Spermatogenesis       Date:  2015-01-07

2.  Ultrastructural correlation of water reabsorption in isolated rat cauda epididymidis.

Authors:  Y C Wong; P Y Wong; C H Yeung
Journal:  Experientia       Date:  1978-04-15

3.  Effects of some pyrazinecarboxamides on sodium transport in frog skin.

Authors:  A W Cuthbert; G M Fanelli
Journal:  Br J Pharmacol       Date:  1978-05       Impact factor: 8.739

4.  The effects of sodium and amiloride on the motility of the caudal epididymal spermatozoa of the rat.

Authors:  P Y Wong; W M Lee; A Y Tsang
Journal:  Experientia       Date:  1981-01-15

5.  Absorptive and secretory functions of the perfused rat cauda epididymidis.

Authors:  P Y Wong; C H Yeung
Journal:  J Physiol       Date:  1978-02       Impact factor: 5.182

6.  Sodium coupled bicarbonate influx regulates intracellular and apical pH in cultured rat caput epididymal epithelium.

Authors:  Wu-Lin Zuo; Sheng Li; Jie-Hong Huang; Deng-Liang Yang; Geng Zhang; Si-Liang Chen; Ye-Chun Ruan; Ke-Nan Ye; Christopher H K Cheng; Wen-Liang Zhou
Journal:  PLoS One       Date:  2011-08-22       Impact factor: 3.240
  6 in total

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