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Literature DB >> 9989584

The intramitochondrial ATP/ADP-ratio controls cytochrome c oxidase activity allosterically.

Abstract

Recently the signal transduction function for oxidative phosphorylation was found to be second order in ADP [Jeneson, J.A.L., Wiseman, R.W., Westerhoff, H.V. and Kushmerick, M.J. (1996) J. Biol. Chem. 271, 27995-279981, but the molecular mechanism of signal transduction remained unclear. Previously we described inhibition of cytochrome c oxidase by intramitochondrial ATP, accompanied by a change of hyperbolic into sigmoidal kinetics. The present study describes a sigmoidal relationship also between the ascorbate respiration of reconstituted cytochrome c oxidase and intraliposomal ADP concentration. Its possible role in the control of oxidative phosphorylation and cell respiration is discussed.

Entities: Chemical

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Year: 1999 PMID： 9989584 DOI： 10.1016/s0014-5793(98)01694-9

Source DB: PubMed Journal: FEBS Lett ISSN： 0014-5793 Impact factor: 4.124

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Cited

38 in total

1. Delta oscillations induced by ketamine increase energy levels in sleep-wake related brain regions.

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Journal: Neuroscience Date: 2011-09-17 Impact factor: 3.590

2. Acquisition of temozolomide chemoresistance in gliomas leads to remodeling of mitochondrial electron transport chain.

Authors: Claudia R Oliva; Susan E Nozell; Anne Diers; Samuel G McClugage; Jann N Sarkaria; James M Markert; Victor M Darley-Usmar; Shannon M Bailey; G Yancey Gillespie; Aimee Landar; Corinne E Griguer
Journal: J Biol Chem Date: 2010-09-24 Impact factor: 5.157

3. Modeling the detailed kinetics of mitochondrial cytochrome c oxidase: Catalytic mechanism and nitric oxide inhibition.

Authors: Venkat R Pannala; Amadou K S Camara; Ranjan K Dash
Journal: J Appl Physiol (1985) Date: 2016-09-15

4. Protein kinase A-mediated phosphorylation modulates cytochrome c oxidase function and augments hypoxia and myocardial ischemia-related injury.

Authors: Subbuswamy K Prabu; Hindupur K Anandatheerthavarada; Haider Raza; Satish Srinivasan; Joseph F Spear; Narayan G Avadhani
Journal: J Biol Chem Date: 2005-11-22 Impact factor: 5.157

Review 5. Heat shock protein expression and change of cytochrome c oxidase activity: presence of two phylogenic old systems to protect tissues in ischemia and reperfusion.

Authors: Sebastian Vogt; Irene Portig; Mark Irqsusi; Volker Ruppert; Petra Weber; Rabia Ramzan
Journal: J Bioenerg Biomembr Date: 2011-08 Impact factor: 2.945

The intramitochondrial ATP/ADP-ratio controls cytochrome c oxidase activity allosterically.

1. Delta oscillations induced by ketamine increase energy levels in sleep-wake related brain regions.

2. Acquisition of temozolomide chemoresistance in gliomas leads to remodeling of mitochondrial electron transport chain.

3. Modeling the detailed kinetics of mitochondrial cytochrome c oxidase: Catalytic mechanism and nitric oxide inhibition.

4. Protein kinase A-mediated phosphorylation modulates cytochrome c oxidase function and augments hypoxia and myocardial ischemia-related injury.

Review 5. Heat shock protein expression and change of cytochrome c oxidase activity: presence of two phylogenic old systems to protect tissues in ischemia and reperfusion.

Review 6. Regulation of skeletal muscle mitochondrial function: genes to proteins.

7. Subfunctionalization of COX4 paralogs in fish.

8. Control of mitochondrial membrane potential and ROS formation by reversible phosphorylation of cytochrome c oxidase.

Review 9. Cytochrome c oxidase dysfunction in oxidative stress.

10. Disruption of insulin signalling preserves bioenergetic competence of mitochondria in ageing Caenorhabditis elegans.