Literature DB >> 9989235

Tripeptidyl-peptidase I is apparently the CLN2 protein absent in classical late-infantile neuronal ceroid lipofuscinosis.

N D Rawlings1, A J Barrett.   

Abstract

We report that fragments of amino acid sequence recently described for tripeptidyl-peptidase I (TPP I) show that it is the rat homologue of the human CLN2 gene product that is deficient in classical late-infantile neuronal ceroid lipofuscinosis. This is unexpected, since the CLN2 protein has been thought to be a carboxyl-dependent endopeptidase, but TPP I is an exopeptidase possibly of serine-type.

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Year:  1999        PMID： 9989235     DOI： 10.1016/s0167-4838(98)00238-6

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  26 in total

1.  Collagenolytic serine-carboxyl proteinase from Alicyclobacillus sendaiensis strain NTAP-1: purification, characterization, gene cloning, and heterologous expression.

Authors:  Naoki Tsuruoka; Toru Nakayama; Masako Ashida; Hisashi Hemmi; Masahiro Nakao; Hiroyuki Minakata; Hiroshi Oyama; Kohei Oda; Tokuzo Nishino
Journal:  Appl Environ Microbiol       Date:  2003-01       Impact factor: 4.792

2.  Aorsin, a novel serine proteinase with trypsin-like specificity at acidic pH.

Authors:  Byung Rho Lee; Masato Furukawa; Koichiro Yamashita; Yurie Kanasugi; Choko Kawabata; Kenichi Hirano; Kenichi Ando; Eiji Ichishima
Journal:  Biochem J       Date:  2003-04-15       Impact factor: 3.857

3.  Murine cathepsin F deficiency causes neuronal lipofuscinosis and late-onset neurological disease.

Authors:  Chi-Hui Tang; Je-Wook Lee; Michael G Galvez; Liliane Robillard; Sara E Mole; Harold A Chapman
Journal:  Mol Cell Biol       Date:  2006-03       Impact factor: 4.272

4.  A mouse model of classical late-infantile neuronal ceroid lipofuscinosis based on targeted disruption of the CLN2 gene results in a loss of tripeptidyl-peptidase I activity and progressive neurodegeneration.

Authors:  David E Sleat; Jennifer A Wiseman; Mukarram El-Banna; Kwi-Hye Kim; Qinwen Mao; Sandy Price; Shannon L Macauley; Richard L Sidman; Michael M Shen; Qi Zhao; Marco A Passini; Beverly L Davidson; Gregory R Stewart; Peter Lobel
Journal:  J Neurosci       Date:  2004-10-13       Impact factor: 6.167

5.  Residual levels of tripeptidyl-peptidase I activity dramatically ameliorate disease in late-infantile neuronal ceroid lipofuscinosis.

Authors:  David E Sleat; Mukarram El-Banna; Istvan Sohar; Kwi-Hye Kim; Kostantin Dobrenis; Steven U Walkley; Peter Lobel
Journal:  Mol Genet Metab       Date:  2008-03-17       Impact factor: 4.797

6.  A critical tryptophan and Ca2+ in activation and catalysis of TPPI, the enzyme deficient in classic late-infantile neuronal ceroid lipofuscinosis.

Authors:  Salomon Kuizon; Kathleen DiMaiuta; Marius Walus; Edmund C Jenkins; Marisol Kuizon; Elizabeth Kida; Adam A Golabek; Daniel O Espinoza; Raju K Pullarkat; Mohammed A Junaid
Journal:  PLoS One       Date:  2010-08-03       Impact factor: 3.752

Review 7.  Molecular background of progressive myoclonus epilepsy.

Authors:  Anna-Elina Lehesjoki
Journal:  EMBO J       Date:  2003-07-15       Impact factor: 11.598

8.  Assessment of disease severity in late infantile neuronal ceroid lipofuscinosis using multiparametric MR imaging.

Authors:  J P Dyke; D Sondhi; H U Voss; D C Shungu; X Mao; K Yohay; S Worgall; N R Hackett; C Hollmann; M E Yeotsas; A L Jeong; B Van de Graaf; I Cao; S M Kaminsky; L A Heier; K D Rudser; M M Souweidane; M G Kaplitt; B Kosofsky; R G Crystal; D Ballon
Journal:  AJNR Am J Neuroradiol       Date:  2012-10-04       Impact factor: 3.825

Review 9.  Endosomal Trafficking in Alzheimer's Disease, Parkinson's Disease, and Neuronal Ceroid Lipofuscinosis.

Authors:  Yasir H Qureshi; Penelope Baez; Christiane Reitz
Journal:  Mol Cell Biol       Date:  2020-09-14       Impact factor: 4.272

10.  Sedolisins, a new class of secreted proteases from Aspergillus fumigatus with endoprotease or tripeptidyl-peptidase activity at acidic pHs.

Authors:  Utz Reichard; Barbara Léchenne; Abdul R Asif; Frank Streit; Eric Grouzmann; Olivier Jousson; Michel Monod
Journal:  Appl Environ Microbiol       Date:  2006-03       Impact factor: 4.792
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