Literature DB >> 9988172

Prevalence of IgG antibodies to Ebola virus in individuals during an Ebola outbreak, Democratic Republic of the Congo, 1995.

K M Busico1, K L Marshall, T G Ksiazek, T H Roels, Y Fleerackers, H Feldmann, A S Khan, C J Peters.   

Abstract

During the 1995 outbreak of Ebola (EBO) hemorrhagic fever in Kikwit, Democratic Republic of Congo, two surveys using a new ELISA for EBO (subtype Zaire) virus antigen were conducted to assess the prevalence of EBO IgG antibodies among residents of Kikwit and the surrounding area. The first study determined the proportion of antibody-positive individuals who were self-identified forest and city workers from the Kikwit area. Serum samples from 9 (2.2%) of 414 workers had IgG EBO antibodies. The second study determined the proportion of EBO antibody-positive individuals who lived in villages surrounding Kikwit. The prevalence of IgG EBO antibodies in this population was 9.3% (151161). The difference in the overall prevalence of EBO antibodies may indicate that villagers have a greater chance of exposure to EBO virus compared with those living in and in close proximity to cities.

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Year:  1999        PMID: 9988172     DOI: 10.1086/514309

Source DB:  PubMed          Journal:  J Infect Dis        ISSN: 0022-1899            Impact factor:   5.226


  34 in total

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Journal:  J Infect Dis       Date:  2018-11-22       Impact factor: 5.226

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Journal:  J Infect Dis       Date:  2018-01-30       Impact factor: 5.226

3.  Profiling the native specific human humoral immune response to Sudan Ebola virus strain Gulu by chemiluminescence enzyme-linked immunosorbent assay.

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5.  Zoonotic risk factors associated with seroprevalence of Ebola virus GP antibodies in the absence of diagnosed Ebola virus disease in the Democratic Republic of Congo.

Authors:  Anna Bratcher; Nicole A Hoff; Reena H Doshi; Adva Gadoth; Megan Halbrook; Patrick Mukadi; Kamy Musene; Benoit Ilunga-Kebela; D'Andre Spencer; Matthew S Bramble; David McIlwan; J Daniel Kelly; Daniel Mukadi; Placide Mbala Kingebeni; Steve Ahuka; Emile Okitolonda-Wemakoy; Jean-Jacques Muyembe-Tamfum; Anne W Rimoin
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6.  High prevalence of both humoral and cellular immunity to Zaire ebolavirus among rural populations in Gabon.

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7.  Persistent infection with ebola virus under conditions of partial immunity.

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8.  Reemerging Sudan Ebola virus disease in Uganda, 2011.

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Journal:  Emerg Infect Dis       Date:  2012-09       Impact factor: 6.883

9.  Ad35 and ad26 vaccine vectors induce potent and cross-reactive antibody and T-cell responses to multiple filovirus species.

Authors:  Roland Zahn; Gert Gillisen; Anna Roos; Marina Koning; Esmeralda van der Helm; Dirk Spek; Mo Weijtens; Maria Grazia Pau; Katarina Radošević; Gerrit Jan Weverling; Jerome Custers; Jort Vellinga; Hanneke Schuitemaker; Jaap Goudsmit; Ariane Rodríguez
Journal:  PLoS One       Date:  2012-12-06       Impact factor: 3.240

10.  Serologic cross-reactivity of human IgM and IgG antibodies to five species of Ebola virus.

Authors:  Adam Macneil; Zachary Reed; Pierre E Rollin
Journal:  PLoS Negl Trop Dis       Date:  2011-06-07
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