| Literature DB >> 9973941 |
P Dal Cin1, L De Smet, R Sciot, B Van Damme, H Van den Berghe.
Abstract
Cytogenetic and molecular cytogenetic analysis is reported in a series of 40 tissue samples from 36 patients with Dupuytren's disease, presenting as palmar and/or finger nodules. No consistent structural chromosome changes could be found. Instead, recurrent clonal numerical abnormalities were demonstrated in 22 of 40 tissue nodules, involving trisomies of chromosome 7 or 8 and loss of the Y chromosome. In addition, we showed that trisomy 7 and trisomy 8 were also present in non-dividing cells.Entities:
Mesh：
Year: 1999 PMID： 9973941 DOI： 10.1016/s0165-4608(98)00126-5
Source DB: PubMed Journal: Cancer Genet Cytogenet ISSN： 0165-4608