Literature DB >> 9973924

Involvement of MLL gene in a t(10;11)(q22;q23) and a t(8;11)(q24;q23) identified by fluorescence in situ hybridization.

A Aventín1, R La Starza, C Martínez, I Wlodarska, M Boogaerts, H Van den Berghe, C Mecucci.   

Abstract

We describe two cases of acute myeloblastic leukemia, classified as M4 and M5 in the French-American-British nomenclature, with an 11q23 rearrangement at karyotypic analysis. The involvement of the MLL gene with two new partner loci on chromosome 10q22 and 8q24, respectively, was demonstrated by fluorescence in situ hybridization using a YAC clone B22B2L.

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Year:  1999        PMID： 9973924     DOI： 10.1016/s0165-4608(98)00110-1

Source DB:  PubMed          Journal:  Cancer Genet Cytogenet        ISSN： 0165-4608


  3 in total

1.  First description of the t(10;11)(q22;q23)/MLL-TET1 translocation in a T-cell lymphoblastic lymphoma, with subsequent lineage switch to acute myelomonocytic myeloid leukemia.

Authors:  Antoine Ittel; Eric Jeandidier; Catherine Helias; Nathalie Perrusson; Catherine Humbrecht; Bruno Lioure; Isabelle Mazurier; Caroline Mayeur-Rousse; Amandine Lavaux; Sylvie Thiebault; Felix Lerintiu; Carine Gervais; Laurent Mauvieux
Journal:  Haematologica       Date:  2013-12       Impact factor: 9.941

2.  Genomic breakpoints and clinical features of MLL-TET1 rearrangement in acute leukemias.

Authors:  Sang-Guk Lee; Sun Young Cho; Min Jin Kim; Seung Hwan Oh; Eun Hae Cho; Sanggyu Lee; Eun Jung Baek; Jung Hye Choi; Stefan K Bohlander; Laurence Lode; Steven Richebourg; Hwi-Joong Yoon; Rolf Marschalek; Claus Meyer; Tae Sung Park
Journal:  Haematologica       Date:  2012-10-25       Impact factor: 9.941

Review 3.  DNMT3A and TET2 in the Pre-Leukemic Phase of Hematopoietic Disorders.

Authors:  Hanae Sato; Justin C Wheat; Ulrich Steidl; Keisuke Ito
Journal:  Front Oncol       Date:  2016-08-22       Impact factor: 6.244
  3 in total

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