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Literature DB >> 9973270

Protein fate in neurodegenerative proteinopathies: polyglutamine diseases join the (mis)fold.

H L Paulson¹.

Abstract

Entities: Chemical Disease

Mesh：

Substances：

Year: 1999 PMID： 9973270 PMCID： PMC1377742 DOI： 10.1086/302269

Source DB: PubMed Journal: Am J Hum Genet ISSN： 0002-9297 Impact factor: 11.025

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34 in total

1. Cleavage of huntingtin by apopain, a proapoptotic cysteine protease, is modulated by the polyglutamine tract.

Authors: Y P Goldberg; D W Nicholson; D M Rasper; M A Kalchman; H B Koide; R K Graham; M Bromm; P Kazemi-Esfarjani; N A Thornberry; J P Vaillancourt; M R Hayden
Journal: Nat Genet Date: 1996-08 Impact factor: 38.330

2. Expanded polyglutamine in the Machado-Joseph disease protein induces cell death in vitro and in vivo.

Authors: H Ikeda; M Yamaguchi; S Sugai; Y Aze; S Narumiya; A Kakizuka
Journal: Nat Genet Date: 1996-06 Impact factor: 38.330

3. Length of huntingtin and its polyglutamine tract influences localization and frequency of intracellular aggregates.

Authors: D Martindale; A Hackam; A Wieczorek; L Ellerby; C Wellington; K McCutcheon; R Singaraja; P Kazemi-Esfarjani; R Devon; S U Kim; D E Bredesen; F Tufaro; M R Hayden
Journal: Nat Genet Date: 1998-02 Impact factor: 38.330

4. Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain.

Authors: M DiFiglia; E Sapp; K O Chase; S W Davies; G P Bates; J P Vonsattel; N Aronin
Journal: Science Date: 1997-09-26 Impact factor: 47.728

5. Intranuclear inclusions of expanded polyglutamine protein in spinocerebellar ataxia type 3.

Authors: H L Paulson; M K Perez; Y Trottier; J Q Trojanowski; S H Subramony; S S Das; P Vig; J L Mandel; K H Fischbeck; R N Pittman
Journal: Neuron Date: 1997-08 Impact factor: 17.173

6. The cerebellar leucine-rich acidic nuclear protein interacts with ataxin-1.

Authors: A Matilla; B T Koshy; C J Cummings; T Isobe; H T Orr; H Y Zoghbi
Journal: Nature Date: 1997-10-30 Impact factor: 49.962

7. Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo.

Authors: E Scherzinger; R Lurz; M Turmaine; L Mangiarini; B Hollenbach; R Hasenbank; G P Bates; S W Davies; H Lehrach; E E Wanker
Journal: Cell Date: 1997-08-08 Impact factor: 41.582

8. Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation.

Authors: S W Davies; M Turmaine; B A Cozens; M DiFiglia; A H Sharp; C A Ross; E Scherzinger; E E Wanker; L Mangiarini; G P Bates
Journal: Cell Date: 1997-08-08 Impact factor: 41.582

9. Polyglutamine expansion as a pathological epitope in Huntington's disease and four dominant cerebellar ataxias.

Authors: Y Trottier; Y Lutz; G Stevanin; G Imbert; D Devys; G Cancel; F Saudou; C Weber; G David; L Tora
Journal: Nature Date: 1995-11-23 Impact factor: 49.962

10. Glutamine repeats as polar zippers: their possible role in inherited neurodegenerative diseases.

Authors: M F Perutz; T Johnson; M Suzuki; J T Finch
Journal: Proc Natl Acad Sci U S A Date: 1994-06-07 Impact factor: 11.205

43 in total

1. Increased T-type Ca2+ channel activity as a determinant of cellular toxicity in neuronal cell lines expressing polyglutamine-expanded human androgen receptors.

Authors: A Sculptoreanu; H Abramovici; A A Abdullah; A Bibikova; V Panet-Raymond; D Frankel; H M Schipper; L Pinsky; M A Trifiro
Journal: Mol Cell Biochem Date: 2000-01 Impact factor: 3.396

2. The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription.

Authors: J S Steffan; A Kazantsev; O Spasic-Boskovic; M Greenwald; Y Z Zhu; H Gohler; E E Wanker; G P Bates; D E Housman; L M Thompson
Journal: Proc Natl Acad Sci U S A Date: 2000-06-06 Impact factor: 11.205

3. Accumulation of mutant huntingtin fragments in aggresome-like inclusion bodies as a result of insufficient protein degradation.

Authors: S Waelter; A Boeddrich; R Lurz; E Scherzinger; G Lueder; H Lehrach; E E Wanker
Journal: Mol Biol Cell Date: 2001-05 Impact factor: 4.138

4. A cell-based assay for aggregation inhibitors as therapeutics of polyglutamine-repeat disease and validation in Drosophila.

Authors: Barbara L Apostol; Alexsey Kazantsev; Simona Raffioni; Katalin Illes; Judit Pallos; Laszlo Bodai; Natalia Slepko; James E Bear; Frank B Gertler; Steven Hersch; David E Housman; J Lawrence Marsh; Leslie Michels Thompson
Journal: Proc Natl Acad Sci U S A Date: 2003-05-01 Impact factor: 11.205

Review 5. From Alzheimer to Huntington: why is a structural understanding so difficult?

Authors: Piero Andrea Temussi; Laura Masino; Annalisa Pastore
Journal: EMBO J Date: 2003-02-03 Impact factor: 11.598

6. Structural characterization of transglutaminase-catalyzed cross-linking between glyceraldehyde 3-phosphate dehydrogenase and polyglutamine repeats.

Authors: Margherita Ruoppolo; Stefania Orrù; Simona Francese; Ivana Caputo; Carla Esposito
Journal: Protein Sci Date: 2003-01 Impact factor: 6.725