| Literature DB >> 9971842 |
G Kuntz-Simon1, T Bashir, J Rommelaere, K Willwand.
Abstract
Minute virus of mice (MVM) shows an oncotropic behavior reflected by its ability to amplify its genome more efficiently in a number of transformed versus normal cells. In vivo and in vitro studies revealed that the major effect of cell transformation on MVM DNA replication occurs at the level of double-stranded replicative-form amplification. In particular, resolution of MVM DNA concatemers into monomers was found to be highly sensitive to neoplastic transformation.Entities:
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Year: 1999 PMID: 9971842 PMCID: PMC104504
Source DB: PubMed Journal: J Virol ISSN: 0022-538X Impact factor: 5.103