Literature DB >> 996503

[The genetics of Gilbert syndrome].

E Penner, W R Mayr, S Djawan, H Seyfried, M Pacher.   

Abstract

Investigation of 19 unrelated patients with Gilbert's syndrome and family studies in 21 first degree relatives of 7 of these patients are in agreement with an autosomal-dominant mode of inheritance with incomplete penetrance. The calculated penetrance in our study is 57%. HLA typing (locus A, B, C) showed a slight, insignificant increase in antigens A11 and BW35. Furthermore, this syndrome did not segregate in parallel with certain haplotypes within families.

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Year:  1976        PMID: 996503

Source DB:  PubMed          Journal:  Schweiz Med Wochenschr        ISSN: 0036-7672


  2 in total

1.  No association between Gilbert's syndrome, the ABO blood groups and the haptoglobin phenotypes.

Authors:  R Platzer; J Bircher
Journal:  Experientia       Date:  1977-09-15

Review 2.  Gilbert's syndrome and drug metabolism.

Authors:  A F Macklon; R L Savage; M D Rawlins
Journal:  Clin Pharmacokinet       Date:  1979 May-Jun       Impact factor: 6.447

  2 in total

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