Literature DB >> 9953

Inhibition of gastric emptying and drug absorption by narcotic analgesics.

W S Nimmo, R C Heading, J Wilson, P Tothill, L F Prescott.   

Abstract

The effect of intramuscular pethidine or diamorphine on gastric emptying and the absorption of orally administered paracetamol was assessed in eight normal subjects. 2 Both drugs produced a significant and striking delay in gastric emptying and absorption of paracetamol. 3 It seems inevitable that pethidine and diamorphine will retard the absorption of other orally administered drugs.

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Year:  1975        PMID： 9953      PMCID： PMC1402648          DOI： 10.1111/j.1365-2125.1975.tb00568.x

Source DB:  PubMed          Journal:  Br J Clin Pharmacol        ISSN： 0306-5251            Impact factor:   4.335


  13 in total

1.  Effects of morphine and other drugs on motility of the terminal ileum.

Authors:  E E DANIEL; W H SUTHERLAND; A BOGOCH
Journal:  Gastroenterology       Date:  1959-04       Impact factor: 22.682

2.  The effect of morphine sulfate on gastric motility; some radiologic observations in man.

Authors:  G M ARDRAN; R S CRONE
Journal:  Gastroenterology       Date:  1957-01       Impact factor: 22.682

3.  Renal insensitivity to frusemide caused by chronic anticonvulsant therapy.

Authors:  S Ahmad
Journal:  Br Med J       Date:  1974-09-14

4.  Gas-liquid chromatographic estimation of paracetamol.

Authors:  L F Prescott
Journal:  J Pharm Pharmacol       Date:  1971-10       Impact factor: 3.765

5.  Pattern of gastric emptying after vagotomy and pyloroplasty.

Authors:  M R Colmer; G M Owen; R Shields
Journal:  Br Med J       Date:  1973-05-26

6.  An evaluation of indium DTPA chelate in the measurement of gastric emptying by scintiscanning.

Authors:  R C Heading; P Tothill; A J Laidlaw; D J Shearman
Journal:  Gut       Date:  1971-08       Impact factor: 23.059

7.  Effect of metoclopramide on gastric emptying during labour.

Authors:  F A Howard; D S Sharp
Journal:  Br Med J       Date:  1973-02-24

8.  Pharmacological modification of gastric emptying: effects of propantheline and metoclopromide on paracetamol absorption.

Authors:  J Nimmo; R C Heading; P Tothill; L F Prescott
Journal:  Br Med J       Date:  1973-03-10

9.  Effect of morphine on some sympathetically innervated effectors.

Authors:  A B CAIRNIE; H W KOSTERLITZ; D W TAYLOR
Journal:  Br J Pharmacol Chemother       Date:  1961-12

10.  Absorption of effervescent aspirin during migraine.

Authors:  G N Volans
Journal:  Br Med J       Date:  1974-11-02
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  64 in total

Review 1.  How useful is paracetamol absorption as a marker of gastric emptying? A systematic literature study.

Authors:  M Willems; A O Quartero; M E Numans
Journal:  Dig Dis Sci       Date:  2001-10       Impact factor: 3.199

2.  A model for size and age changes in the pharmacokinetics of paracetamol in neonates, infants and children.

Authors:  B J Anderson; G A Woollard; N H Holford
Journal:  Br J Clin Pharmacol       Date:  2000-08       Impact factor: 4.335

Review 3.  Adverse effects of systemic opioid analgesics.

Authors:  S A Schug; D Zech; S Grond
Journal:  Drug Saf       Date:  1992 May-Jun       Impact factor: 5.606

Review 4.  Gastric emptying and anaesthesia.

Authors:  W S Nimmo
Journal:  Can J Anaesth       Date:  1989-05       Impact factor: 5.063

Review 5.  Palliative medicine.

Authors:  R J George; A L Jennings
Journal:  Postgrad Med J       Date:  1993-06       Impact factor: 2.401

6.  [On the toxicology of carbromal. II. Pharmacokinetics of carbromal and its hypnotically active metabolites in the rat (author's transl)].

Authors:  H W Vohland; S Hadisoemarto; B Wanke
Journal:  Arch Toxicol       Date:  1977-08-09       Impact factor: 5.153

7.  The effect of anesthetic technique on early postoperative gastric emptying: comparison of propofol-remifentanil and opioid-free sevoflurane anesthesia.

Authors:  Jakob Walldén; Sven-Egron Thörn; Asa Lövqvist; Lisbeth Wattwil; Magnus Wattwil
Journal:  J Anesth       Date:  2006       Impact factor: 2.078

Review 8.  Drug absorption in gastrointestinal disease with particular reference to malabsorption syndromes.

Authors:  R L Parsons
Journal:  Clin Pharmacokinet       Date:  1977 Jan-Feb       Impact factor: 6.447

9.  Gastric emptying following brain injury: effects of choice of sedation and intracranial pressure.

Authors:  C J McArthur; T Gin; I M McLaren; J A Critchley; T E Oh
Journal:  Intensive Care Med       Date:  1995-07       Impact factor: 17.440

10.  Relationship between the phasic period of interdigestive migrating contraction and the systemic bioavailability of acetaminophen in dogs.

Authors:  K Sagara; H Mizuta; M Ohshiko; M Shibata; K Haga
Journal:  Pharm Res       Date:  1995-04       Impact factor: 4.200
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