Literature DB >> 9950743

Hidden neural networks.

A Krogh1, S K Riis.   

Abstract

A general framework for hybrids of hidden Markov models (HMMs) and neural networks (NNs) called hidden neural networks (HNNs) is described. The article begins by reviewing standard HMMs and estimation by conditional maximum likelihood, which is used by the HNN. In the HNN, the usual HMM probability parameters are replaced by the outputs of state-specific neural networks. As opposed to many other hybrids, the HNN is normalized globally and therefore has a valid probabilistic interpretation. All parameters in the HNN are estimated simultaneously according to the discriminative conditional maximum likelihood criterion. The HNN can be viewed as an undirected probabilistic independence network (a graphical model), where the neural networks provide a compact representation of the clique functions. An evaluation of the HNN on the task of recognizing broad phoneme classes in the TIMIT database shows clear performance gains compared to standard HMMs tested on the same task.

Mesh:

Year:  1999        PMID: 9950743     DOI: 10.1162/089976699300016764

Source DB:  PubMed          Journal:  Neural Comput        ISSN: 0899-7667            Impact factor:   2.026


  4 in total

1.  Prediction of lipoprotein signal peptides in Gram-negative bacteria.

Authors:  Agnieszka S Juncker; Hanni Willenbrock; Gunnar Von Heijne; Søren Brunak; Henrik Nielsen; Anders Krogh
Journal:  Protein Sci       Date:  2003-08       Impact factor: 6.725

2.  Prediction of the disulfide-bonding state of cysteines in proteins at 88% accuracy.

Authors:  Pier Luigi Martelli; Piero Fariselli; Luca Malaguti; Rita Casadio
Journal:  Protein Sci       Date:  2002-11       Impact factor: 6.725

3.  An evolutionary method for learning HMM structure: prediction of protein secondary structure.

Authors:  Kyoung-Jae Won; Thomas Hamelryck; Adam Prügel-Bennett; Anders Krogh
Journal:  BMC Bioinformatics       Date:  2007-09-21       Impact factor: 3.169

4.  A Hidden Markov Model method, capable of predicting and discriminating beta-barrel outer membrane proteins.

Authors:  Pantelis G Bagos; Theodore D Liakopoulos; Ioannis C Spyropoulos; Stavros J Hamodrakas
Journal:  BMC Bioinformatics       Date:  2004-03-15       Impact factor: 3.169

  4 in total

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